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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   ESRRB Antibody   

ESRRB Antibody

  • WB - ESRRB Antibody ASC11474
    Western blot analysis of ESRRB in human heart tissue lysate with ESRRB antibody at 1 µg/mL in (A) the absence and (B) the presence of blocking peptide.
  • IHC - ESRRB Antibody ASC11474
    Immunohistochemistry of ESRR8 in human heart tissue with ESRR8 antibody at 5 µg/mL.
  • IF - ESRRB Antibody ASC11474
    Immunofluorescence of ESRRB in human heart tissue with ESRRB antibody at 20 µg/mL.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O95718
Other Accession NP_004443, 238550159
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype IgG
Calculated MW 56208 Da
Application Notes ESRRB antibody can be used for detection of ESRRB by Western blot at 1 µg/mL. Antibody can also be used for immunohistochemistry starting at 5 µg/mL. For immunofluorescence start at 5 µg/mL.
Additional Information
Gene ID 2103
Target/Specificity ESRRB;
Reconstitution & Storage ESRRB antibody can be stored at 4℃ for three months and -20℃, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
PrecautionsESRRB Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms ERRB2, ESRL2, NR3B2
Function Nuclear receptor, may regulate ESR1 transcriptional activity. Induces the expression of PERM1 in the skeletal muscle.
Cellular Location Nucleus {ECO:0000255|PROSITE- ProRule:PRU00407, ECO:0000269|PubMed:18775884}
Research Areas
Citations (0)

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ESRRB Antibody: The estrogen-related receptor beta (ESRRB) was initially identified in mouse embryonic carcinoma stem cells and was found to be expressed exclusively in trophoblast progenitor cells between days 6.5 and 7.5 post coitum. Recent studies have shown that ESRRB is part of an POU5F1/Oct4-centered protein interaction network in embryonic stem (ES) cells. It is thought to interact with other ES transcription factors such as NANOG within this network, activating POU5F1 transcription and thereby sustaining self-renewal and pluripotency in ES cells.


Pettersson K, Svensson K, Mattsson R, et al. Expression of a novel member of estrogen response element-binding nuclear receptors is restricted to the early stages of chorion formation during mouse embryogenesis. Mech. Dev. 1996; 54:211-23.
van den Berg DL, Snoek T, Mullin NP, et al. An Oct4-centered protein interaction network in embryonic stem cells. Cell Stem Cell 2010; 6:369-81.
Zhang X, Zhang J, Wang T, et al. Esrrb activates Oct4 transcription and sustains self-renewal and pluripotency in embryonic stem cells. J. Biol. Chem. 2008; 283:35825-33.

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$ 310.00
Cat# ASC11474
(40 western blots)
Availability: 5-7days
Bulk Size
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