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DBX2 Antibody

     
  • WB - DBX2 Antibody ASC11489
    Western blot analysis of WDR18 in rat lung tissue lysate with WDR18 antibody at (A) 1 and (B) 2 µg/mL.
    detail
  • IHC - DBX2 Antibody ASC11489
    Immunohistochemistry of DBX2 in human kidney tissue with DBX2 antibody at 5 µg/mL.
    detail
  • IF - DBX2 Antibody ASC11489
    Immunofluorescence of DBX2 in human kidney tissue with DBX2 antibody at 20 µg/mL.
    detail
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, IF, E
Primary Accession Q6ZNG2
Other Accession NP_001004329, 116174748
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype IgG
Calculated MW 36555 Da
Application Notes DBX2 antibody can be used for detection of DBX2 by Western blot at 1 and 2 µg/mL. Antibody can also be used for immunohistochemistry starting at 5 µg/mL. For immunofluorescence start at 5 µg/mL.
Additional Information
Gene ID 440097
Target/Specificity DBX2; DBX2 antibody is human specific. At least two isoforms of DBX2 are known to exist; this antibody will only detect the shortest isoform.
Reconstitution & Storage DBX2 antibody can be stored at 4℃ for three months and -20℃, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
PrecautionsDBX2 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name DBX2
Cellular Location Nucleus {ECO:0000255|PROSITE-ProRule:PRU00108}.
Research Areas
Citations (0)
citation

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Background

DBX2 Antibody: DBX2 is a member of the developing brain homeobox (DBX) protein family, but while the related protein DBX1 is expressed in various regions of the developing brain, DBX2 shows a more restricted pattern of expression in the brain, and is also expressed in some mesenchymal cells such as limb buds and tooth germs. It is thought that DBX1 and DBX2 promote the development of a subset of interneurons, some of which help mediate left-right coordination of locomotor activity. In Xenopus, DBX2 is involved in primary neurogenesis and early neural plate patterning, and is thought to act as a cross-repressive partner of NKX6-2 in the patterning of the ventral neural tube.

References

Shoji H, Ito T, Wakamatsu Y, et al. Regionalized expression of the Dbx family homeobox genes in the embryonic CNS of the mouse. Mech. Dev. 56:25-39.
Lacin H, Zhu Y, Wilson BA, et al. Dbx mediates neuronal specification and differentiation through cross-repressive, lineage-specific interactions with eve and hb9. Development 2009; 136:3257-66.
Ma P, Zhao S, Zeng W, et al. Xenopus Dbx2 is involved in primary neurogenesis and early neural plate patterning. Biochem. Biophys. Res. Commun. 2011; 412:170-4.

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$ 379.00
Cat# ASC11489
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