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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   TTYH1 Antibody   

TTYH1 Antibody

  • WB - TTYH1 Antibody ASC11492
    Western blot analysis of TTYH1 in Raji cell lysate with TTYH1 antibody at (A) 1 and (B) 2 µg/mL.
  • ICC - TTYH1 Antibody ASC11492
    Immunocytochemistry of TTYH1 in Raji cells with TTYH1 antibody at 5 µg/mL.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9H313
Other Accession NP_001005367, 53831989
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype IgG
Calculated MW 49051 Da
Application Notes TTYH1 antibody can be used for detection of TTYH1 by Western blot at 1 - 2 µg/mL. Antibody can also be used for immunocytochemistry starting at 5 µg/mL.
Additional Information
Gene ID 57348
Target/Specificity TTYH1; TTYH1 antibody is human specific. Multiple isoforms of TTYH1 are known to exist.
Reconstitution & Storage TTYH1 antibody can be stored at 4℃ for three months and -20℃, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
PrecautionsTTYH1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name TTYH1
Function Probable chloride channel. May be involved in cell adhesion (By similarity).
Cellular Location Cell membrane; Multi-pass membrane protein
Tissue Location Expressed in brain, eye, ovary and testis, and at lower levels in muscle, placenta, liver and lung
Research Areas
Citations (0)

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TTYH1 Antibody: TTYH1 is a member of the tweety family of proteins, a family of chloride anion channels containing five transmembrane regions. TTYH1 is a Ca2+-independent, volume-sensitive large conductance chloride (Cl-) channel. TTYH1 is primarily expressed in neural tissue and upregulated in astrocytoma, glioma, and several other cancers. Recent experiments have shown that TTYH1 is an integral endoplasmic reticulum (ER) membrane protein involved in cell proliferation and is thought to play an essential role in embryonic cell growth, possibly through the Ca2+ storage/release process in ER membranes during early development.


Campbell HD, Kamei M, Caludianos C, et al. Human and mouse homologues of the Drosophila melanogaster tweety (tty) gene: a novel gene family encoding predicted transmembrane proteins. Genomics 2000; 68:89-92.
Matthews CA, Shaw JE, Hooper JA, et al. Expression and evolution of the mammalian brain gene Ttyh1. J. Neurochem. 100:693-707
Kumada T, Yamanaka Y, Kitano A, et al. Ttyh1, a Ca2+-binding protein localized to the endoplasmic reticulum, is required for early embryonic development. Dev. Dyn. 2010; 239:2233-45.

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$ 330.00
Cat# ASC11492
Availability: 5-7days
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