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TCTEX1D1 Antibody

     
  • WB - TCTEX1D1 Antibody ASC11516
    Western blot analysis of TCTEX1D1 in K562 cell lysate with TCTEX1D1 antibody at 1 µg/mL in (A) the absence and (B) the presence of blocking peptide.
    detail
  • IF - TCTEX1D1 Antibody ASC11516
    Immunofluorescence of TCTEX1D1 in K562 cells with TCTEX1D1 antibody at 20 µg/mL.
    detail
  • SPECIFICATION
  • CITATIONS
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IF, E
Primary Accession Q8N7M0
Other Accession NP_689878, 239735600
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype IgG
Calculated MW 20 kDa
Application Notes TCTEX1D1 antibody can be used for detection of TCTEX1D1 by Western blot at 1 µg/mL. For immunofluorescence start at 20 µg/mL.
Additional Information
Gene ID 200132
Target/Specificity TCTEX1D1; At least three isoforms are known to exist; this antibody will detect the two largest isoforms. TCTEX1D1 is predicted to not cross-react with other members of the TCTEX-type family.
Reconstitution & Storage TCTEX1D1 antibody can be stored at 4℃ for three months and -20℃, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
PrecautionsTCTEX1D1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name DYNLT5
Synonyms TCTEX1D1
Research Areas
Citations (0)
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Background

TCTEX1D1 Antibody: Dyneins are multi-subunit, high molecular weight ATPases that interact with microtubules to generate force by converting the chemical energy of ATP into the mechanical energy of movement. Cytoplasmic or axonemal Dynein is an approximately 12 subunit complex of two heavy chains, two intermediate chains to anchor Dynein to its cargo, four smaller intermediate chains and several light chains. It performs functions necessary for cell survival such as organelle transport and centrosome assembly. TCTEX1 is a cytoplasmic dynein light chain found in a complex with Na+ CP type X (SCN10A). TCTEX1D1, also called TCTEX1 domain containing 1, belongs to the dynein light chain TCTEX-type family. Its function is still under investigation.

References

He Y, Francis F, Myers KA, et al. Role of cytoplasmic dynein in the axonal transport of microtubules and neurofilaments. J. Cell Biol. 2005; 168:697-703.
Li J, Lee WL, and Cooper JA. NudEL targets dynein to microtubule ends through LIS1. Nat. Cell Biol. 2005; 7:686-90.
Watanabe TK, Fujiwara T, Shimizu F, et al. Cloning, expression, and mapping of TCTEL1, a putative human homologue of murine Tcte1 to 6q. Cytogenet. Cell Genet. 1996; 73:153-6.
Chuang JZ, Yeh TY, Bollati F, et al. The dynein light chain Tctex-1 has a dynein-independent role in actin remodeling during neurite outgrowth. Dev. Cell 2005; 9:75-86.

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$ 379.00
Cat# ASC11516
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