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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   TCTEX1D3 Antibody   

TCTEX1D3 Antibody

  • WB - TCTEX1D3 Antibody ASC11518
    Western blot analysis of TCTEX1D3 in EL4 cell lysate with TCTEX1D3 antibody at 1 µg/mL in (A) the absence and (B) the presence of blocking peptide.
  • IF - TCTEX1D3 Antibody ASC11518
    Immunofluorescence of TCTEX1D3 in human testis tissue with TCTEX1D3 antibody at 20 µg/mL.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q8IZS6
Other Accession NP_777570, 28372535
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype IgG
Calculated MW 22 kDa
Application Notes TCTEX1D3 antibody can be used for detection of TCTEX1D3 by Western blot at 1 µg/mL. For immunofluorescence start at 20 µg/mL.
Additional Information
Gene ID 6991
Target/Specificity TCTE3; TCTEX1D3 is predicted to not cross-react with other members of the TCTEX-type family
Reconstitution & Storage TCTEX1D3 antibody can be stored at 4℃ for three months and -20℃, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
PrecautionsTCTEX1D3 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name TCTE3
Synonyms TCTEX1D3
Function May be an accessory component of axonemal dynein and cytoplasmic dynein 1. Candidate for involvement in male sterility (By similarity).
Cellular Location Cytoplasm, cytoskeleton. Cytoplasmic granule. Membrane; Peripheral membrane protein. Note=Found on the surface of sperm tail. Stored in cytoplasmic granules during spermatogenesis (By similarity).
Tissue Location Expressed predominantly in testis. Also expressed in brain, lung and trachea
Research Areas
Citations (0)

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TCTEX1D3 Antibody: Dyneins are multi-subunit, high molecular weight ATPases that interact with microtubules to generate force by converting the chemical energy of ATP into the mechanical energy of movement. Cytoplasmic or axonemal Dynein is an approximately 12 subunit complex of two heavy chains, two intermediate chains to anchor Dynein to its cargo, four smaller intermediate chains and several light chains. It performs functions necessary for cell survival such as organelle transport and centrosome assembly. TCTEX1 is a cytoplasmic dynein light chain found in a complex with Na+ CP type X (SCN10A). TCTEX1D3, also called TCTE3, has been identified as a gene responsible for congenital diaphragmatic hernia (CDH).


He Y, Francis F, Myers KA, et al. Role of cytoplasmic dynein in the axonal transport of microtubules and neurofilaments. J. Cell Biol. 2005; 168:697-703.
Li J, Lee WL, and Cooper JA. NudEL targets dynein to microtubule ends through LIS1. Nat. Cell Biol. 2005; 7:686-90.
Watanabe TK, Fujiwara T, Shimizu F, et al. Cloning, expression, and mapping of TCTEL1, a putative human homologue of murine Tcte1 to 6q. Cytogenet. Cell Genet. 1996; 73:153-6.
Chuang JZ, Yeh TY, Bollati F, et al. The dynein light chain Tctex-1 has a dynein-independent role in actin remodeling during neurite outgrowth. Dev. Cell 2005; 9:75-86.

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$ 310.00
Cat# ASC11518
(40 western blots)
Availability: 5-7days
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