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SGSM3 Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IF, E |
|---|---|
| Primary Accession | Q96HU1 |
| Other Accession | CAQ08933, 168985143 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Calculated MW | 82 kDa |
| Application Notes | SGSM3 antibody can be used for detection of SGSM3 by Western blot at 1 µg/mL. For immunofluorescence start at 20 µg/mL. |
| Gene ID | 27352 |
|---|---|
| Target/Specificity | SGSM3; Multiple isoforms of SGSM3 are known to exist. SGSM3 antibody is predicted to not cross react with other SGSM family proteins. |
| Reconstitution & Storage | SGSM3 antibody can be stored at 4℃ for three months and -20℃, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Precautions | SGSM3 Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | SGSM3 (HGNC:25228) |
|---|---|
| Function | May play a cooperative role in NF2-mediated growth suppression of cells. |
| Cellular Location | Cytoplasm. |
| Tissue Location | Widely expressed.. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
SGSM3 Antibody: Small G proteins such as RAP and RAB proteins are the key molecules in intracellular signal transduction and vesicle transportation. A novel protein family small G protein signaling modulator (SGSM) consisting of three members SGSM1-3 bind to RAP and RAB family proteins. All three SGSM proteins possess both a RUN domain and a TBC domain. Little is known of the exact function of SGSM3.
References
Bar-Sagi D and Hall A. Ras and Rho GTPases: a family reunion. Cell 2000; 103:227-38.
Colicelli J. Human ras superfamily proteins and related GTPases. Sci. STKE 2004; 250:RE13.
Yang H, Sasaki T, Minoshima S, et al. Identification of three novel proteins (SGSM1, 2, 3) which modulate small G protein (RAP and RAB)-mediated signaling pathway. Genomics 2007; 90:249-60.
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