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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   TNFAIP2 Antibody   

TNFAIP2 Antibody

     
  • WB - TNFAIP2 Antibody ASC11554
    Western blot analysis of TNFAIP2 in K562 cell lysate with TNFAIP2 antibody at 1 µg/mL in (A) the absence and (B) the presence of blocking peptide.
    detail
  • IF - TNFAIP2 Antibody ASC11554
    Immunofluorescence of TNFAIP2 in K562 cells with TNFAIP2 antibody at 20 µg/mL.
    detail
  • SPECIFICATION
  • CITATIONS
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  • BACKGROUND
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IF, E
Primary Accession Q03169
Other Accession NP_006282, 26051240
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype IgG
Calculated MW 72 kDa
Application Notes TNFAIP2 antibody can be used for detection of TNFAIP2 by Western blot at 1 µg/mL. For immunofluorescence start at 20 µg/mL.
Additional Information
Gene ID 7127
Target/Specificity TNFAIP2; At least two isoforms of TNFAIP2 are known to exist; this antibody will detect both isoforms. This antibody is predicted to not cross-react with TNFAIP3.
Reconstitution & Storage TNFAIP2 antibody can be stored at 4℃ for three months and -20℃, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
PrecautionsTNFAIP2 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name TNFAIP2
Function May play a role as a mediator of inflammation and angiogenesis.
Research Areas
Citations (0)
citation

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Background

TNFAIP2 Antibody: TNFAIP2, also known as B94, is a TNF-a-regulated gene that is expressed in endothelial cells, peripheral blood cells, and mature sperm. Recently, elevated TNFAIP2 expression was observed in nasopharyngeal carcinoma, and high expression of TNFAIP2 was significantly correlated with higher levels of cell migration, invasion and metastasis, suggesting that TNFAIP2 may serve as a useful prognostic indicator for nasopharyngeal carcinoma. TNFAIP2 has also been implicated as part of the viral-sensing circuit of the innate immune response.

References

Wolf FW, Sarma V, Deldin M, et al. B94, a primary response gene inducible by tumor necrosis factor-alpha, is expressed in developing hematopoietic cells and the sperm acrosome. J. Biol. Chem. 1994; 269:3633-40.
Chen LC, Chen CC, Liang Y, et al. A novel role for TNFAIP2: its correlation with invasion and metastasis in nasopharyngeal carcinoma. Mod. Pathol. 2011; 24:175-84.
Chevrier N, Mertins P, Artyomov MN, et al. Systematic discovery of TLR signaling components delineates viral-sensing circuits. Cell 147:853-67.

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$ 379.00
Cat# ASC11554
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