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CHCHD7 Antibody

     
  • WB - CHCHD7 Antibody ASC11585
    Western blot analysis of CHCHD7 in rat liver tissue lysate with CHCHD7 antibody at 1 µg/mL in (A) the absence and (B) the presence of blocking peptide.
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  • SPECIFICATION
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession Q9BUK0
Other Accession NP_077276, 64464338
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype IgG
Calculated MW Predicted: 11 kDa
Application Notes CHCHD7 antibody can be used for detection of CHCHD7 by Western blot at 1 - 2 µg/mL.
Additional Information
Gene ID 79145
Target/Specificity CHCHD7; Three alternatively spliced transcript variants have been observed. CHCHD7 is predicted to not cross-react to other members of the CHCHD family.
Reconstitution & Storage CHCHD7 antibody can be stored at 4℃ for three months and -20℃, stable for up to one year.
PrecautionsCHCHD7 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CHCHD7
Cellular Location Mitochondrion intermembrane space.
Research Areas
Citations (0)
citation

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Background

CHCHD7 Antibody: CHCHD7 is a newly identified member of a multifamily of proteins containing a conserved (coiled coil 1)-(helix 1)-(coiled coil 2)-(helix 2) domain. Northern blot analysis revealed that the gene is ubiquitously expressed. Its biological function is unknown and the gene has hitherto not been associated with neoplasia. CHCHD7 and PLAG1 are located head-to-head about 500 bp apart in 8q12. A chromosomal aberration involving CHCHD7 is found in salivary gland pleiomorphic adenomas, the most common benign epithelial tumors of the salivary gland.

References

Asp J, Persson F, Kost-Alimova M, et al. CHCHD7-PLAG1 and TCEA1-PLAG1 gene fusions resulting from cryptic, intrachromosomal 8q rearrangements in pleomorphic salivary gland adenomas. Genes Chromosomes Cancer 2006; 45:820-8.
Nishimura S, Watanabe T, Mizoshita K, et al. Genome-wide association study identified three major QTL for carcass weight including the PLAG1-CHCHD7 QTN for stature in Japanese Black cattle. BMC Genet. 2012; 13:40.
Matsuyama A, Hisaoka M, and Hashimoto H. PLAG1 expression in cutaneous mixed tumors: an immunohistochemical and molecular genetic study. Virchows Arch. 2011; 459:539-45.

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$ 379.00
Cat# ASC11585
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