|Application ||WB, E|
|Other Accession||NP_055605, 45237195|
|Calculated MW||Predicted: 89 kDa|
|Application Notes||JAKMIP2 antibody can be used for detection of JAKMIP2 by Western blot at 1 - 2 µg/mL.|
|Target/Specificity||JAKMIP2; At least four isoforms of JAKMIP2 are known to exist; this antibody will detect all four isoforms. JAKMIP2 antibody is predicted to not cross-react with JAKMIP1.|
|Reconstitution & Storage||JAKMIP2 antibody can be stored at 4℃ for three months and -20℃, stable for up to one year.|
|Precautions||JAKMIP2 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||JAMIP2, KIAA0555, NECC1|
|Cellular Location||Golgi apparatus|
|Tissue Location||Highly expressed in brain, moderately expressed in thymus, spleen and lung, and weakly expressed in kidney, liver and peripheral blood lymphocytes. Also expressed in adrenal and pituitary glands, as well as testis|
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Provided below are standard protocols that you may find useful for product applications.
JAKMIP2 Antibody: JAKMIP2, also known as neuroendocrine long coiled-coil protein 1 (NECC1), is a member of the JAKMIP family of proteins whose members are thought play a role in JAK1 signaling and the regulation of microtubule cytoskeleton rearrangements. JAKMIP2 is expressed predominantly in neuronal cells but unlike JAKMIP1, JAKMIP2 localizes to the Golgi complex. It has been suggested that JAKMIP2 may play important roles in the control of the regulated secretory pathway.
Steindler C, Li Z, Algarte M, et al. Jamip1 (Marlin-1) defines a family of proteins interacting with Janus kinases and microtubules. J. Biol. Chem. 2004; 279:43168-77.
Cruz-Garcia D, Vazquez-Martinez R, Peinado JR, et al. Identification and characterization of two novel (neuro)endocrine long coiled-coil proteins. FEBS Lett. 2007; 581:3149-56.
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