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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   TYK2 Antibody   

TYK2 Antibody

  • WB - TYK2 Antibody ASC11596
    Western blot analysis of TYK2 in human small intestine tissue lysate with TYK2 antibody at (A) 1 and (B) 2 µg/mL
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P29597
Other Accession NP_003322, 187608615
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype IgG
Calculated MW Predicted: 131 kDa
Application Notes TYK2 antibody can be used for detection of TYK2 by Western blot at 1 - 2 µg/mL.
Additional Information
Gene ID 7297
Target/Specificity TYK2; At least three isoforms of TYK2 are known to exist; this antibody only detects the two longest isoforms.
Reconstitution & Storage TYK2 antibody can be stored at 4℃ for three months and -20℃, stable for up to one year.
PrecautionsTYK2 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name TYK2
Function Probably involved in intracellular signal transduction by being involved in the initiation of type I IFN signaling. Phosphorylates the interferon-alpha/beta receptor alpha chain.
Tissue Location Observed in all cell lines analyzed. Expressed in a variety of lymphoid and non-lymphoid cell lines
Research Areas
Citations (0)

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TYK2 Antibody: TYK2 is a member of the Janus kinases (JAKs) protein families. TYK2 associates with the cytoplasmic domain of type I and type II cytokine receptors and promulgate cytokine signals by phosphorylating receptor subunits and is also a component of both the type I and type III interferon signaling pathways. As such, it may play a role in anti-viral immunity. A mutation in this gene has been associated with hyperimmunoglobulin E syndrome (HIES) - a primary immunodeficiency characterized by elevated serum immunoglobulin E.


Strobl B, Stoiber D, Sexl V, et al. Tyrosine kinase 2 (TYK2) in cytokine signalling and host immunity. Front. Biosci. 2011; 17:3214-32.

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$ 310.00
Cat# ASC11596
(40 western blots)
Availability: 5-7days
Bulk Size
Seasonal Special on Bulk Order
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