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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   SDPR Antibody   

SDPR Antibody

  • WB - SDPR Antibody ASC11628
    Western blot analysis of SDPR in HeLa cell lysate with SDPR antibody at (A) 1 and (B) 2 µg/mL
  • IHC - SDPR Antibody ASC11628
    Immunohistochemistry of SDPR in spleen tissue with SDPR antibody at 5 µg/ml.
  • IF - SDPR Antibody ASC11628
    Immunofluorescence of SDPR in human spleen tissue with SDPR antibody at 20 µg/ml.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O95810
Other Accession NP_004648, 4759082
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype IgG
Calculated MW 47 kDa
Application Notes SDPR antibody can be used for detection of SDPR by Western blot at 1 - 2 µg/mL.
Additional Information
Gene ID 8436
Target/Specificity SDPR; It is predicted to not cross-react with other members of the cavin family.
Reconstitution & Storage SDPR antibody can be stored at 4℃ for three months and -20℃, stable for up to one year.
PrecautionsSDPR Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name SDPR {ECO:0000312|EMBL:AAD17795.1}
Function May play a role in targeting PRKCA to caveolae.
Cellular Location Cytoplasm, cytosol. Membrane, caveola. Note=Colocalizes with CAV1 to caveolae
Tissue Location Highly expressed in heart and lung, and expressed at lower levels in brain, kidney, liver, pancreas, placenta, and skeletal muscle.
Research Areas
Citations (0)

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SDPR Antibody: The serum deprivation-response protein (SDPR) is a calcium-independent phospholipid-binding protein whose expression is increased in serum-starved cells. SDPR is a substrate for protein kinase C (PKC) phosphorylation and recruits the polymerase I and transcript release factor (PTRF) to caveolae. Removal of this protein causes caveolae loss and its over-expression results in caveolae deformation and membrane tubulation. Both SDPR and PTRF, as well as the other member of the cavin family PRKCDBP were down regulated in breast cancer cell lines and breast tumor tissue, suggesting that expression of the cavin family proteins could be a useful prognostic indicator of breast cancer progression.


Gustincich S, Vatta P, Goruppi S, et al. The human serum deprivation response gene (SDPR) maps to 2q32-q33 and codes for a phosphatidylserine-binding protein. Genomics 1999; 57:120-9.
Hansen CG, Bright NA, Howard G, et al. SDPR induces membrane curvature and functions in the formation of caveolae. Nat. Cell Biol. 2009; 11:807-14.
Bai L, Deng X, Li Q, et al. Down-regulation of the cavin family proteins in breast cancer. J. Cell Biochem. 2012; 113:322-8.

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$ 310.00
Cat# ASC11628
(40 western blots)
Availability: 5-7days
Bulk Size
Seasonal Special on Bulk Order
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