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>   home   >   Products   >   Primary Antibodies   >   Cell Biology   >   ERRF Antibody   

ERRF Antibody

     
  • IF - ERRF Antibody ASC11638
    Immunofluorescence of NELF in mouse brain tissue with NELF Antibodyat 20 µg/mL.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, IF, E
Primary Accession Q8NEQ6
Other Accession NP_849162, 149563
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Isotype IgG
Calculated MW Predicted: 19 kDa

Observed: 15 kDa
Application Notes ERRF Antibody can be used for detection of ERRF by Western blot at 1 μg/mL.
Additional Information
Gene ID 149563
Target/Specificity ERRF antibody was raised against a 15 amino acid peptide near the carboxy terminus of human ERRF .

The immunogen is located within the last 50 amino acids of ERRF.
Reconstitution & Storage ERRF antibody can be stored at 4℃ for three months and -20℃, stable for up to one year.
PrecautionsERRF Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name C1orf64
Research Areas
Citations (0)

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Background

ERRF Antibody: The estrogen receptor-related factor (ERRF) is a recently identified protein whose expression is upregulated in multiple cell lines and primary breast cancer tumors. Increased ERRF expression was significantly associated with ER or progesterone receptor (PR) positivity even in HER2-negative tumors. This higher ERRF expression correlated with better disease-free survival and overall survival. In two ER-positive breast cancer cell lines, knockdown of ERRF suppressed cell growth in vitro and tumorigenesis in xenograft models, suggesting that ERRF plays a role in estrogen-ER-mediated breast cancer cell growth and may thus be a potential therapeutic target.

References

Su D, Fu X, Fan S, et al. Role of ERRF, a novel ER-related nuclear factor, in the growth control of ER-positive human breast cancer cells. Am. J. Pathol. 2012; 180:1189-201.


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$ 320.00
Cat# ASC11638
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