|Application ||WB, IHC, IF, E|
|Other Accession||NP_054750, 28965|
|Reactivity||Human, Mouse, Rat|
|Calculated MW||Predicted: 68 kDa |
Observed: 68 kDa
|Application Notes||SLC27A6 antibody can be used for detection of SLC27A6 by Western blot at 1 - 2 μg/mL. Antibody can also be used for Immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL.|
|Target/Specificity||SLC27A6 antibody was raised against a 16 amino acid peptide near the amino terminus of human SLC27A6.|
The immunogen is located within amino acids 180 - 230 of SLC27A6.
|Reconstitution & Storage||SLC27A6 antibody can be stored at 4℃ for three months and -20℃, stable for up to one year.|
|Precautions||SLC27A6 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||ACSVL2, FACVL2, FATP1|
|Function||Involved in translocation of long-chain fatty acids (LFCA) across the plasma membrane. Thought to function as the predominant fatty acid protein transporter in heart.|
|Cellular Location||Membrane; Multi-pass membrane protein. Cell membrane, sarcolemma Note=In heart is exclusively located on the sarcolemma in areas juxtaposed with small blood vessels where it colocalizes CD36|
|Tissue Location||Strongly expressed in heart and localizes to cardiac myocytes. Expressed at moderate levels in placenta, testis, and adrenal glands. Expressed at very low levels in kidney, bladder and uterus.|
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Provided below are standard protocols that you may find useful for product applications.
SLC27A6 Antibody: The solute carrier family 27 (fatty acid transporter), member 6 (SLC27A6) is a member of the fatty acid transport protein family (FATP), which are involved in the uptake of long-chain fatty acids. SLC27A6 is principally expressed in the heart on the sarcolemma and colocalizes with CD36, another molecule involved in the uptake of long chain fatty acids.
Gimeno RE, Ortegon AM, Patel S, et al. Characterization of a heart-specific fatty acid transport protein. J. Biol. Chem. 2003;278:16039-44.
Fisher RM and Gertow K. Fatty acid transport proteins and insulin resistance. Curr. Opin. Lipidol. 2005; 16:173-8.
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