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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   CNRIP1 Antibody   

CNRIP1 Antibody

     
  • WB - CNRIP1 Antibody ASC11644
    Western blot analysis of CNRIP1 in human brain tissue lysate with CNRIP1 antibody at 1 µg/mL.
  • IHC - CNRIP1 Antibody ASC11644
    Immunohistochemistry of CNRIP1 in rat brain tissue with CNRIP1 antibody at 2.5 µg/ml.
  • IF - CNRIP1 Antibody ASC11644
    Immunofluorescence of CNRIP1 in rat brain tissue with CNRIP1 antibody at 20 µg/ml.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, IF, E
Primary Accession Q96F85
Other Accession NP_056278, 25927
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype IgG
Calculated MW Predicted: 18 kDa

Observed: 16 kDa
Application Notes CNRIP1 antibody can be used for detection of CNRIP1 by Western blot at 1 - 2 μg/mL.
Additional Information
Gene ID 25927
Target/Specificity CNRIP1 antibody was raised against a 15 amino acid peptide near the center of human CNRIP1.

The immunogen is located within amino acids 50 - 100 of CNRIP1.
Reconstitution & Storage CNRIP1 antibody can be stored at 4℃ for three months and -20℃, stable for up to one year.
PrecautionsCNRIP1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CNRIP1
Synonyms C2orf32
Function Isoform 1 suppresses cannabinoid receptor CNR1-mediated tonic inhibition of voltage-gated calcium channels. Isoform 2 does not have this effect.
Research Areas
Citations (0)

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Background

CNRIP1 Antibody: The CNRIP1 (cannabinoid receptor interacting protein 1) protein is a G-protein coupled receptor which interacts with the C-terminal tail of cannabinoid receptor 1 (CB1) and is thought to play a role in synaptic plasticity, analgesia, appetite, and neuroprotection. One isoform of CNRIP1, CNRIP1a, modulates the constitutive CB1 receptor activity in the central nervous system (CNS), while the role of the shorter isoform CNRIP1b is yet unknown. CNRIP1 has been suggested as a potential target for CNS drug discovery.

References

Niehaus JL, Liu Y, Wallis KT, et al. CB1 cannabinoid receptor activity is modulated by the cannabinoid receptor interacting protein CRIP 1a. Mol. Pharmacol. 2007; 72:1557-66.
Smith TH, Sim-Selley LJ, and Selley DE. Cannabinoid CB1 receptor-interacting proteins: novel targets for central nervous system drug discovery. Br. J. Pharm. 2010; 160:454-66.

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$ 320.00
Cat# ASC11644
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