Rift Valley Fever Virus Nucleocapsid Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| E |
---|---|
Primary Accession | Q9QKA6 |
Other Accession | YP_003848707, 302596926 |
Reactivity | Virus |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | IgG |
Calculated MW | Predicted: 27 kDa |
Application Notes | RVF virus nucleocapsid antibody can detect 10ng RVF virus nucleocapsid peptide in ELISA at 1 µg/mL. |
Gene ID | 9538291 |
---|---|
Target/Specificity | NP; |
Reconstitution & Storage | Rift Valley Fever Virus Nucleocapsid antibody can be stored at 4℃ for three months and -20℃, stable for up to one year. |
Precautions | Rift Valley Fever Virus Nucleocapsid Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Rift Valley Fever Virus Nucleocapsid Antibody: Rift Valley Fever (RFV) virus is an arthropod-borne virus endemic to Africa that infects humans and animals that is transmitted predominantly by mosquitoes (1). During human infections, symptoms can range from benign fever to severe encephalitis and fatal hepatitis with hemorrhagic fever. The Bunyaviridae family of viruses to which the RVF virus belongs are spherical enveloped viruses with a tripartite RNA genome of negative or ambisense polarity (2). The three segments are referred to as the L, M, and S segments. The L and M segments are negative polarity and code fore the L-dependent RNA polymerase and glycoprotein precursor respectively. The S segment is of ambisense polarity and encodes the nucleoprotein and non-structural proteins (3).
References
Morrill JC and McClain DJ. Epidemiology and pathogenesis of the Rift Valley fever and other phleboviruses, p. 281-93 in H Fraenkel-Conrat and RR Wagner (ed.) The viruses. Plenum Press, New York, NY.
Schmaljohn C and Hooper JW. Bunyaviridae: the viruses and their replication, 4th ed. Lippincott Williams & Wilkins, Philadelphia, PA.
Giorgi C, Accardi L, Nicoletti M, et al. Sequences and coding strategies of the S RNAs of Toscana and Rift Valley fever viruses compared to those of Punta Toro, Sicilian sandfly fever, and Uukuniemi viruses. Virology 1991; 180:738-53.
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