La Crosse Virus Nucleocapsid Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| E |
---|---|
Primary Accession | Q8JPR0 |
Other Accession | AAM94389, 22212786 |
Reactivity | Virus |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | IgG |
Calculated MW | Predicted: 26 kDa |
Application Notes | La Crosse virus nucleocapsid antibody can detect 10 ng La Crosse virus nucleocapsid peptide in ELISA at 1 µg/mL. |
Gene ID | 956556 |
---|---|
Target/Specificity | N; |
Reconstitution & Storage | Rift Valley Fever Virus Nucleocapsid antibody can be stored at 4℃ for three months and -20℃, stable for up to one year. |
Precautions | La Crosse Virus Nucleocapsid Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | N |
---|---|
Function | Encapsidates the genome protecting it from nucleases. The encapsidated genomic RNA is termed the nucleocapsid (NC) and serves as template for transcription and replication. Seems to participate in the nuclear relocalization of host PABP1, thereby inhibiting host cellular translation (By similarity). |
Cellular Location | Virion. Note=Internal protein of virus particle. |
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Provided below are standard protocols that you may find useful for product applications.
Background
La Crosse Virus Nucleocapsid Antibody: La Crosse virus (LCV) is a single-stranded RNA virus that can cause encephalitis in humans and is transmitted predominantly by mosquitoes. It is often mistaken for herpes simplex encephalitis (1). During human infections, LCV initially presents as a nonspecific summertime illness with fever, headache, nausea, vomiting and lethargy. Death occurs in less than 1% of clinical cases.
References
McJunkin JE, de los Reyes EC, Irazuzta JE, et al. La Crosse encephalitis in children. N. Eng. J. Med. 2001; 344:801-7.
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