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IL-17RA Antibody

  • WB - IL-17RA Antibody ASC11676
    Western blot analysis of IL17RA in A20 cell lysate with IL17RA antibody at 1 µg/mL.
  • IHC - IL-17RA Antibody ASC11676
    Immunohistochemistry of IL-17RA in human spleen tissue with IL-17RA antibody at 2.5 µg/ml.
  • IF - IL-17RA Antibody ASC11676
    Immunofluorescence of IL-17RA in human spleen tissue with IL-17RA antibody at 20 µg/ml.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q96F46
Other Accession NP_055154, 23238208
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype IgG
Calculated MW Predicted: 95 kDa

Observed: 135 kDa
Application Notes IL-17RA antibody can be used for detection of IL-17RA by Western blot at 1 - 2 µg/mL.
Additional Information
Gene ID 23765
Target/Specificity IL17RA; IL-17RA antibody is human, mouse and rat reactive. Multiple isoforms of IL-17RA are known to exist. This antibody is predicted to not cross-react with other IL-17 receptor subunits.
Reconstitution & Storage IL-17RA antibody can be stored at 4℃ for three months and -20℃, stable for up to one year.
PrecautionsIL-17RA Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name IL17RA
Synonyms IL17R
Function Receptor for IL17A, IL17F and, in dimer with IL17RE, for IL17C. Binds its IL17A ligand with low affinity, suggesting that additional components are involved in IL17A-induced signaling.
Cellular Location Isoform 1: Membrane; Single- pass type I membrane protein
Tissue Location Widely expressed.
Research Areas
Citations (0)

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IL-17RA Antibody: Interleukin 17A (IL-17A) is a proinflammatory cytokine secreted by activated T-lymphocytes (1). It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. IL-17RA is a ubiquitous type I membrane glycoprotein that binds with low affinity to IL-17A and IL-17F (1,2). IL-17A and its receptor play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis (3,4). Defects in IL-17RA are the cause of familial candidiasis type 5 (CANDF5) which is a rare disorder with altered immune responses and impaired clearance of fungal infections (5).


Yao Z, Painter SL, Fanslow WC, et al. Human IL-17: a novel cytokine derived from T cells. J. Immunol. 1995; 155: 5483-6.
Yao Z, Fanslow WC, Seldin MF, et al. Herpesvirus saimiri encodes a new cytokine, IL-17, which binds to a novel cytokine receptor. Immunity 1995; 3:811-21.
Rickel EA, Siegel LA, Yoon BR, et al. Identification of functional roles for both IL-17RB and IL-17RA in mediating IL-25-induced activities. J. Immunol. 2008;181:4299-310.
Wang M, Wang L, Ren T, et al. IL-17A/IL-17RA interaction promoted metastasis of osteosarcoma cells. Cancer Biol. Ther. 2012;14(2).

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$ 310.00
Cat# ASC11676
(40 western blots)
Availability: 5-7days
Bulk Size
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