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B2M Antibody

  • WB - B2M Antibody ASC11683
    Western blot analysis of B2M in SK-N-SH cell lysate with B2M antibody at 1 µg/mL in (A) the absence and (B) the presence of blocking peptide.
  • IHC - B2M Antibody ASC11683
    Immunohistochemistry of B2M in mouse brain tissue with B2M antibody 5 µg/mL.
  • IF - B2M Antibody ASC11683
    Immunofluorescence of B2M in mouse brain tissue with B2M antibody at 20 µg/mL.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P61769
Other Accession NP_004039, 4757826
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype IgG
Calculated MW Predicted: 13 kDa

Observed: 12 kDa
Application Notes B2M antibody can be used for detection of B2M by Western blot at 1 - 2 µg/mL.
Additional Information
Gene ID 567
Target/Specificity B2M; B2M antibody is human reactive.
Reconstitution & Storage B2M antibody can be stored at 4℃ for three months and -20℃, stable for up to one year.
PrecautionsB2M Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name B2M
Function Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system.
Cellular Location Secreted. Note=Detected in serum and urine
Research Areas
Citations (0)

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B2M Antibody: Beta2-microglobulin (B2M) is a principal component of the Major Histocompatibility Complex (MHC) class I molecule, a ternary membrane protein complex that displays fragments derived from proteolyzed cytosolic proteins on the surface of cells for recognition by the surveillance immune system (1,2). B2M is involved in the presentation of peptide antigens to the immune system and plays a critically important role in immune system function (3). It is expressed on nearly all nucleated cells and contains one Ig-like C1-type (immunoglobulin-like) domain (2,3). Mutations in the Beta 2-microglobulin gene can enhance the progression of malignant melanoma and osteoarthropathy (4,5).


Krangel MS, Orr HT, and Strominger JL. Assembly and maturation of HLA-A and HLA-B antigens in vivo. Cell 1979; 18:979-91.
Skjodt K, Welinder KG, Crone M, et al. Isolation and characterization of chicken and turkey beta 2-microglobulin. Mol. Immunol. 1986; 23:1301-9.
Ohashi K. Pathogenesis of beta2-microglobulin amyloidosis. Pathol. Int. 2001; 51:1-10.
Blum C, Graham A, Yousefzadeh M, et al. The expression ratio of Map7/B2M is prognostic for survival in patients with stage II colon cancer. Int. J. Oncol. 2008; 33:579-84.

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$ 310.00
Cat# ASC11683
(40 western blots)
Availability: 5-7days
Bulk Size
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