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TFPI Antibody

  • WB - TFPI Antibody ASC11684
    Western blot analysis of TFPI in rat small intestine tissue lysate with TFPI antibody at 1 µg/mL.
  • IHC - TFPI Antibody ASC11684
    Immunohistochemistry of TFPI in rat small intestine tissue with TFPI antibody at 5 µg/mL.
  • IF - TFPI Antibody ASC11684
    Immunofluorescence of TFPI in rat small intestine tissue with TFPI antibody at 20 µg/mL.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P10646
Other Accession NP_006278, 5454114
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype IgG
Calculated MW Predicted: 33 kDa

Observed: 30 kDa
Application Notes TFPI antibody can be used for detection of TFPI by Western blot at 1 - 2 µg/mL.
Additional Information
Gene ID 7035
Target/Specificity TFPI; TFPI antibody is human, mouse and rat reactive. At least two isoforms of TFPI are known to exist; this antibody will detect both isoforms.
Reconstitution & Storage TFPI antibody can be stored at 4℃ for three months and -20℃, stable for up to one year.
PrecautionsTFPI Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms LACI, TFPI1
Function Inhibits factor X (X(a)) directly and, in a Xa-dependent way, inhibits VIIa/tissue factor activity, presumably by forming a quaternary Xa/LACI/VIIa/TF complex. It possesses an antithrombotic action and also the ability to associate with lipoproteins in plasma.
Cellular Location Isoform Alpha: Secreted.
Tissue Location Mostly in endothelial cells.
Research Areas
Citations (0)

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TFPI Antibody: Tissue factor pathway inhibitor (TFPI), also known as lipoprotein-associated coagulation inhibitor, is a protease inhibitor that regulates the tissue factor (TF)-dependent pathway of blood coagulation (1). TFPI is glycosylated and predominantly found in the vascular endothelium and plasma in both free forms and complexed with plasma lipoproteins. The coagulation process initiates with the formation of a factor VIIa-TF complex, which proteolytically activates additional proteases (factors IX and X) and ultimately leads to the formation of a fibrin clot. TFPI inhibits the activated factor X and VIIa-TF proteases in an autoregulatory loop (1).


Broze GJ Jr and Girard TJ. Tissue factor pathway inhibitor: structure-function. Front. Biosci. 17:262-80.

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$ 310.00
Cat# ASC11684
(40 western blots)
Availability: 5-7days
Bulk Size
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