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>   home   >   Products   >   Primary Antibodies   >   Immunology   >   CD160 Antibody    

CD160 Antibody

  • WB - CD160 Antibody  ASC11698
    Western blot analysis of CD160 in K562 cell lysate with CD160 antibody at 1 µg/ml in (A) the absence and (B) the presence of blocking peptide.
  • IF - CD160 Antibody  ASC11698
    Immunofluorescence of CD160 in Jurkat cells tissue with CD160 antibody at 5 µg/mL.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O95971
Other Accession NP_008984, 5901910
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Isotype IgG
Calculated MW Predicted: 20 kDa

Observed: 25kDa
Application Notes CD160 antibody can be used for detection of CD160 by Western blot at 1 - 2 µg/ml.
Additional Information
Gene ID 11126
Target/Specificity CD160; CD160 antibody is human and mouse reactive. Multiple isoforms of CD160 are known to exist.
Reconstitution & Storage CD160 antibody can be stored at 4℃ for three months and -20℃, stable for up to one year.
PrecautionsCD160 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CD160
Synonyms BY55
Function Receptor showing broad specificity for both classical and non-classical MHC class I molecules.
Cellular Location Cell membrane; Lipid-anchor, GPI-anchor.
Tissue Location Expressed in spleen, peripheral blood, and small intestine. Expression is restricted to functional NK and T cytotoxic lymphocytes
Research Areas
Citations (0)

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CD160, also known as BY55, is a lipid-anchored cell membrane glycoprotein that contains one immunoglobulin-like domain (1). It is expressed in small intestine, spleen and functional NK and T cytotoxic lymphocytes (1,2). CD160 exists as a disulfide-linked homomultimer that functions as a receptor for MHC (major histocompatability complex) molecules and is thought to regulate the function of NK cells (2,3). Additionally, CD160 interacts with TNFRSF14 and, via this interaction, is able to negatively regulate CD4+ T cell activation, indicating a role in immune system regulation (4).


Anumanthan A, Bensussan A, Boumsell L, et al. Cloning of BY55, a novel Ig superfamily member expressed on NK cells, CTL, and intestinal intraepithelial lymphocytes. J. Immunol. 1998; 161:2780-90.
Agrawal S, Marquet J, Freeman GJ, et al. Cutting edge: MHC class I triggering by a novel cell surface ligand costimulates proliferation of activated human T cells. J. Immunol. 1999; 162:1223-6.
Le Bouteiller P, Tabiasco J, Polgar B, et al. CD160: a unique activating NK cell receptor. Immunol. Lett. 2011;138:93-6
Chabot S, Jabrane-Ferrat N, Bigot K, et al. A novel antiangiogenic and vascular normalization therapy targeted against human CD160 receptor. J. Exp. Med. 2011; 208:973-86.

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$ 310.00
Cat# ASC11698
(40 western blots)
Availability: 5-7days
Bulk Size
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