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SOGA1 Antibody

  • WB - SOGA1 Antibody  ASC11703
    Western blot analysis of SOGA1 in Hela cell lysate with SOGA1 antibody at (A) 1 and (B) 2 µg/ml.
  • IF - SOGA1 Antibody  ASC11703
    Immunofluorescence of SOGA1 in HeLa cells with SOGA1 antibody at 5 µg/mL.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O94964
Other Accession NP_954650, 66773344
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype IgG
Calculated MW Predicted: 183 kDa

Observed: 200kDa
Application Notes SOGA1 antibody can be used for detection of SOGA1 by Western blot at 1 - 2 µg/ml.
Additional Information
Gene ID 140710
Target/Specificity SOGA1; SOGA1 antibody is human specific. At least four isoforms of SOGA1 are known to exist.
Reconstitution & Storage SOGA1 antibody can be stored at 4℃ for three months and -20℃, stable for up to one year.
PrecautionsSOGA1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name SOGA1
Synonyms C20orf117, KIAA0889, SOGA
Function Regulates autophagy by playing a role in the reduction of glucose production in an adiponectin- and insulin-dependent manner.
Cellular Location C-terminal 80 kDa form: Secreted. Note=Secreted in primary hepatocyte-conditioned media.
Research Areas
Citations (0)

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The recently identified protein suppressor of glucose by autophagy protein 1 (SOGA1) has been found to be involved in the regulation of autophagy (1). SOGA1 is thought to contribute to adiponectin-mediated insulin-dependent inhibition of autophagy during the activation of adenosine monophosphate kinase (AMPK) (1,2). SOGA1 contains an internal signal peptide that enables the secretion of a circulating fragment of SOGA1, providing a surrogate marker for intracellular SOGA1 levels (2). Knockdown of SOGA1 elevated glucose production in primary hepatocytes indicates that SOGA1 is an inhibitor of glucose production. It thus might be useful as a novel therapeutic target for diabetes (3).


Cowherd RB, Asmar MM, Alderman JM, et al. Adiponectin lowers glucose production by increasing SOGA. Am. J. Pathol. 2010; 177:1936-45.
Madi T, Balamurugan K, Bombardi R, et al. The determination of tissue-specific DNA methylation patterns in forensic biofluids using bisulfite modification and pyrosequencing. Electrophoresis 2012; 33:1736-45.
Forbes JM. The physiological deadlock between AMPK and gluconeogenesis: SOGA, a novel protein, may provide the key. Am. J. Pathol. 2010; 177:1600-2.

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$ 330.00
Cat# ASC11703
Availability: 5-7days
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