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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   ADROPIN Antibody   

ADROPIN Antibody

     
  • WB - ADROPIN Antibody ASC11716
    Western blot analysis of ADROPIN in human brain tissue lysate with ADROPIN antibody at 2 µg/ml in (A) the absence and (B) the presence of blocking peptide.
  • IHC - ADROPIN Antibody ASC11716
    Immunohistochemistry of ADROPIN in human brain tissue with ADROPIN antibody at 5 µg/mL.
  • IF - ADROPIN Antibody ASC11716
    Immunofluorescence of ADROPIN in human brain tissue with ADROPIN antibody at 20 µg/mL.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, IF, E
Primary Accession Q6UWT2
Other Accession NP_940975, 58218977
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype IgG
Calculated MW Predicted: 8 kDa

Observed: 16 kDa
Application Notes ADROPIN antibody can be used for detection of ADROPIN by Western blot at 1 - 2 µg/ml. Antibody can also be used for Immunohistochemistry starting at 5 µg/mL. For immunofluorescence start at 20 µg/mL.
Additional Information
Gene ID 375704
Target/Specificity ENHO; ADROPIN antibody is human, mouse and rat reactive. Despite its predicted molecular weight, ADROPIN often migrates at a higher than expected molecular weight in SDS-PAGE.
Reconstitution & Storage ADROPIN antibody can be stored at 4℃ for three months and -20℃, stable for up to one year.
PrecautionsADROPIN Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name ENHO
Synonyms C9orf165
Function Involved in the regulation of glucose homeostasis and lipid metabolism.
Cellular Location Secreted.
Tissue Location Expressed in liver and brain.
Research Areas
Citations (0)

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Background

ADROPIN is a recently identified protein that has been implicated in the maintenance of energy homeostasis and insulin resistance (1-3). ADROPIN expression is regulated by energy status and dietary nutrient content and is altered by obesity and regulates the expression of hepatic lipogenic genes and adipose tissue peroxisome proliferator-activated receptor gamma (PPAR-gamma) (1). ADROPIN levels increase with dietary fat content (2). ADROPIN has also been proposed to play a role in the regulation of endothelial function (3).

References

Kumar KG, Trevaskis JL, Lam DD, et al. Identification of Adropin as a secreted factor linking dietary macronutrient intake with energy homeostasis and lipid metabolism. Cell Metab. 2008; 8:468-81.
Kumar KG, Zhang J, Gao S, et al. Adropin deficiency is associated with increased adiposity and insulin resistance. Obesity 2012; 1394-402.
Lovren F, Pan Y, Quan A, et al. Adropin is a novel regulator of endothelial function. Circulation 2010; 122:S185-92.

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$ 320.00
Cat# ASC11716
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