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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   MAP1LC3C Antibody   

MAP1LC3C Antibody

  • WB - MAP1LC3C Antibody ASC11728
    Western blot analysis of MAP1LC3C in human brain tissue lysate with MAP1LC3C antibody at 1 µg/ml in (A) the absence and (B) the presence of blocking peptide.
  • IHC - MAP1LC3C Antibody ASC11728
    Immunohistochemistry of MAP1LC3C in human brain tissue with MAP1LC3C antibody at 5 µg/mL.
  • IF - MAP1LC3C Antibody ASC11728
    Immunofluorescence of MAP1LC3C in human brain tissue with MAP1LC3C antibody at 20 µg/mL.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9BXW4
Other Accession NP_001004343, 51972260
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype IgG
Calculated MW Predicted: 16 kDa

Observed: 16 kDa
Application Notes MAP1LC3C antibody can be used for detection of MAP1LC3C by Western blot at 1 - 2 µg/ml. Antibody can also be used for Immunohistochemistry starting at 5 µg/mL. For immunofluorescence start at 20 µg/mL.
Additional Information
Gene ID 440738
Target/Specificity MAP1LC3C; MAP1LC3C antibody is human, mouse and rat reactive. Multiple isoforms MAP1LC3C are known to exist. MAP1LC3C antibody is predicted to not cross-react with MAP1LC3A or MAP1LC3B.
Reconstitution & Storage MAP1LC3C antibody can be stored at 4℃ for three months and -20℃, stable for up to one year.
PrecautionsMAP1LC3C Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Function Ubiquitin-like modifier that plays a crucial role in antibacterial autophagy (xenophagy) through the selective binding of CALCOCO2. Recruites all ATG8 family members to infecting bacteria such as S.Typhimurium.
Cellular Location Cytoplasm, cytoskeleton. Endomembrane system; Lipid-anchor. Cytoplasmic vesicle, autophagosome membrane; Lipid-anchor. Note=LC3-II binds to the autophagic membranes
Tissue Location Most abundant in placenta, lung and ovary.
Research Areas
Citations (0)

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Microtubule-associated proteins (MAPs) regulate microtubule stability and play critical roles in neuronal development and plasticity (1). MAP1LC3C belongs to the MAP1 LC3 family of proteins that form mature complexes with MAP1A and MAP1B which are thought to be important in the formation and development of axons and dendrites (2). MAP1LC3C is one of three isoforms of MAP1LC3, the mammalian homolog of yeast ATG8, an essential autophagy protein. These isoforms exhibit distinct expression patterns and MAP1LC3C, like MAP1LC3A but not MAP1LC3B, is post-translationally modified, suggesting the three isoforms may have different physiological functions (3).


Mandelkow E and Mandelkow EM. Microtubules and microtubule-associated proteins. Curr. Opin. Cell Biol. 1995; 7:72-81.
Halpain S and Dehmelt L. The MAP1 family of microtubule-associated proteins. Genome Biol. 2006; 7:224.
He H, Dang Y, Dai F, et al. Post-translational modifications of three members of the human MAP1LC3 family and detection of a novel type of modification for MAP1LC3B. J. Biol. Chem. 2003; 278:29278-87.

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$ 310.00
Cat# ASC11728
(40 western blots)
Availability: 5-7days
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