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CCR7 Antibody

  • WB - CCR7 Antibody ASC11750
    Western blot analysis of CCR7 in human spleen tissue lysate with CCR7 antibody at 1 µg/ml.
  • IHC - CCR7 Antibody ASC11750
    Immunohistochemistry of CCR7 in human spleen tissue with CCR7 antibody at 5 µg/mL.
  • IF - CCR7 Antibody ASC11750
    Immunofluorescence of CCR7 in human spleen tissue with CCR7 antibody at 20 µg/mL.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P32248
Other Accession NP_001829, 4502641
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype IgG
Calculated MW Predicted: 42 kDa

Observed: 42 kDa
Application Notes CCR7 antibody can be used for detection of CCR7 by Western blot at 1 - 2 µg/ml. Antibody can also be used for Immunohistochemistry starting at 5 µg/mL. For immunofluorescence start at 20 µg/mL.
Additional Information
Gene ID 1236
Target/Specificity CCR7; CCR7 antibody is human specific. CCR7 antibody is predicted to not cross-react with other CCR proteins.
Reconstitution & Storage CCR7 antibody can be stored at 4℃ for three months and -20℃, stable for up to one year.
PrecautionsCCR7 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CCR7
Synonyms CMKBR7, EBI1, EVI1
Function Receptor for the MIP-3-beta chemokine. Probable mediator of EBV effects on B-lymphocytes or of normal lymphocyte functions.
Cellular Location Cell membrane; Multi-pass membrane protein.
Tissue Location Expressed in various lymphoid tissues and activated B- and T-lymphocytes, strongly up-regulated in B-cells infected with Epstein-Barr virus and T-cells infected with herpesvirus 6 or 7
Research Areas
Citations (0)

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The CCR7 protein is a member of the G protein-coupled receptor family. This receptor was identified as a gene induced by the Epstein-Barr virus (EBV), and is thought to be a mediator of EBV effects on B lymphocytes. This receptor is expressed in various lymphoid tissues and activates B and T lymphocytes. It has been shown to control the migration of memory T cells to inflamed tissues, as well as stimulate dendritic cell maturation (1,2). The chemokine (C-C motif) ligand 19 (CCL19) has been reported to be a specific ligand of this receptor (3).


Birkenbach M, Josefsen K, Yalamanchil R, et al. Epstein-Barr virus-induced genes: first lymphocyte-specific G protein-coupled peptide receptors. J. Virol. 1993; 67:2209-20.
Forster R, Davalos-Misslitz AC, and Rot A. CCR7 and its ligands: balancing immunity and tolerance. Nat. Rev. Immunol. 2008; 8:362-71.
Yoshida R, Imai T, Hieshima K, et al. Molecular cloning of a novel human CC chemokine EBI1-ligand chemokine that is a specific functional ligand for EBI1, CCR7. J. Biol. Chem. 1997; 272:13803-9.

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$ 310.00
Cat# ASC11750
(40 western blots)
Availability: 5-7days
Bulk Size
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