Sin Nombre Virus Nucleocapsid Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| E |
---|---|
Primary Accession | Q9E1J8 |
Other Accession | AAG03030, 9944924 |
Reactivity | Virus |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | IgG |
Calculated MW | N/A KDa |
Application Notes | Sin Nombre virus nucleocapsid antibody can detect 10ng Sin Nombre virus nucleocapsid peptide in ELISA at 1 µg/ml. |
Gene ID | 2943142 |
---|---|
Target/Specificity | SNVsSgp1; |
Reconstitution & Storage | Sin Nombre Nucleocapsid antibody can be stored at 4℃ for three months and -20℃, stable for up to one year. |
Precautions | Sin Nombre Virus Nucleocapsid Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Background
Sin Nombre virus (SNV) is a rodent-borne hantavirus of the family Bunyaviridae, an enveloped, negative-sense RNA viruses with a tripartite genome that can cause hantavirus pulmonary syndrome (HPS) (1). The hantavirus nucleocapsid protein plays several roles in viral replication and assembly, and is the major antigen in humoral responses in humans and mice (2). Within the bunyviridae family, the nucleocapsid protein also functions as an RNA chaperone facilitating the formation of the stable genomic RNA “panhandle” and is thought to aid in the replication of bunyavirus RNA (3).
References
Spiropoulou CF, Morzunov S, Feldmann H, et al. Genome structure and variability of a virus causing hantavirus pulmonary syndrome. Virology 1994; 200:715-23.
Tischler ND, Rosemblatt M, and Valenzuela PD. Characterization of cross-reactive and serotype-specific epitopes on the nucleocapsid proteins of hantaviruses. Virus Res. 2008; 135:1-9.
Mir MA and Panganiban AT. The bunyavirus nucleocapsid protein is an RNA chaperone: possible roles in viral RNA panhandle formation and genome replication. RNA 2006; 12:272-82.
If you have used an Abcepta product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at tech@abcepta.com.