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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   UCP1 Antibody   

UCP1 Antibody

  • WB - UCP1 Antibody ASC11762
    Western blot analysis of UCP1 in HeLa cell lysate with UCP1 antibody at 1 µg/ml.
  • IHC - UCP1 Antibody ASC11762
    Immunohistochemistry of UCP1 in human liver tissue with UCP1 antibody at 2.5 µg/mL.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P25874
Other Accession NP_068605, 11225256
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype IgG
Calculated MW Predicted: 34 kDa

Observed: 36 kDa
Application Notes UCP1 antibody can be used for detection of UCP1 by Western blot at 1 - 2 µg/ml. Antibody can also be used for Immunohistochemistry starting at 2.5 µg/mL.
Additional Information
Gene ID 7350
Target/Specificity UCP1; UCP1 antibody is human, mouse and rat reactive.
Reconstitution & Storage UCP1 antibody can be stored at 4℃ for three months and -20℃, stable for up to one year.
PrecautionsUCP1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name UCP1
Synonyms SLC25A7, UCP
Function UCP are mitochondrial transporter proteins that create proton leaks across the inner mitochondrial membrane, thus uncoupling oxidative phosphorylation from ATP synthesis. As a result, energy is dissipated in the form of heat.
Cellular Location Mitochondrion inner membrane; Multi-pass membrane protein
Tissue Location Brown adipose tissue.
Research Areas
Citations (0)

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The mitochondrial brown fat uncoupling protein 1 (UCP1) is a member of the family of mitochondrial anion carrier proteins (MACP) (1). UCPs separate oxidative phosphorylation from ATP synthesis with energy dissipated as heat, also referred to as the mitochondrial proton leak. UCPs facilitate the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane. They also reduce the mitochondrial membrane potential in mammalian cells (1). UCP1 is expressed only in brown adipose tissue, a specialized tissue which functions to produce heat (1).


1. Rial E, Gonzalez-Barroso MM, Fleury C, et al. The structure and function of the brown fat uncoupling protein UCP1: current status. Biofactors 1998; 8:209-19.

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$ 310.00
Cat# ASC11762
(40 western blots)
Availability: 5-7days
Bulk Size
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