|Application ||WB, IHC-P, IF, E|
|Other Accession||NP_001138502, 222537754|
|Reactivity||Human, Mouse, Rat|
|Calculated MW||Predicted: 65, 186 kDa |
Observed: 60, 240 kDa
|Application Notes||TOPAZ1 antibody can be used for detection of TOPAZ1 by Western blot at 1 - 2 µg/ml. Antibody can also be used for Immunohistochemistry at 5 µg/mL. For Immunoflorescence start at 20 µg/mL.|
|Target/Specificity||TOPAZ1; TOPAZ1 antibody is human, mouse and rat reactive. At least three isoforms of TOPAZ1 are known to exist.|
|Reconstitution & Storage||TOPAZ1 antibody can be stored at 4℃ for three months and -20℃, stable for up to one year.|
|Precautions||TOPAZ1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Cellular Location||Cytoplasm, cytosol.|
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Provided below are standard protocols that you may find useful for product applications.
The testis and ovary specific PAZ domain containing 1 (TOPAZ1) protein is a highly conserved protein that is highly expressed in the gonads during germ cell meiosis, suggesting that it may play a role in germ cell development (1). It contains a PAZ domain and a zinc finger domain and is exclusively expressed in adult testis and fetal ovary.
Baillet A, Le Bouffant R, Volff JN, et al. TOPAZ1, a novel germ cell-specific expressed gene conserved during evolution across vertebrates. PLoS One 2011; 6:e26950.
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