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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   CRH Antibody   

CRH Antibody

  • WB - CRH Antibody ASC11801
    Western blot analysis of CRH in human placenta tissue lysate with CRH antibody at (A) 1 and (B) 2 µg/ml.
  • IHC - CRH Antibody ASC11801
    Immunohistochemistry of CRH in human brain tissue with CRH antibody at 5 µg/mL.
  • IF - CRH Antibody ASC11801
    Immunofluorescence of CRH in human brain tissue with CRH antibody at 20 µg/mL.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P06850
Other Accession NP_000747, 4503041
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype IgG
Calculated MW Predicted: 22 kDa

Observed: 29 kDa
Application Notes CRH antibody can be used for detection of CRH by Western blot at 1 - 2 µg/ml. Antibody can also be used for Immunohistochemistry at 5 µg/mL. For Immunoflorescence start at 20 µg/mL.
Additional Information
Gene ID 1392
Target/Specificity CRH; CRH antibody is human specific.
Reconstitution & Storage CRH antibody can be stored at 4℃ for three months and -20℃, stable for up to one year.
PrecautionsCRH Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CRH
Function This hormone from hypothalamus regulates the release of corticotropin from pituitary gland.
Cellular Location Secreted.
Research Areas
Citations (0)

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Corticotropin-releasing hormone (CRH) is secreted by the paraventricular nucleus (PVN) of the hypothalamus in response to stress (1). In addition to production in the hypothalamus, this protein is also synthesized in peripheral tissues, such as T lymphocytes and is highly expressed in the placenta where it is a marker that determines the length of gestation and the timing of parturition and delivery. A rapid increase in circulating levels of the hormone occurs at the onset of parturition, suggesting that, in addition to its metabolic functions, this protein may act as a trigger for parturitio (2). Marked reduction in this protein has been observed in association with Alzheimer disease (3).


Maras PM and Baram TZ. Sculpting the hippocampus from within: stress, spines, and CRH. Trends Neurosci. 2012; 315-24.
Vrachnis N, Malamas FM, Sifakis S, et al. Immune aspects and myometrial actions of progesterone and CRH in labor. Clin. Dev. Immunol. 2012; 937618.
Leake A, Perry EK, Perry RH, et al. Neocortical concentrations of neuropeptides in senile dementia of the Alzheimer and Lewy body type: comparison with Parkinson’s disease and severity correlations. Biol. Psychiatry 1991; 29:357-64.

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$ 310.00
Cat# ASC11801
(40 western blots)
Availability: 5-7days
Bulk Size
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