Register or Login
  • All
  • Uniprot Id
  • Catalog #
  • Peptide Sequence
>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   PIK3C3 Antibody   

PIK3C3 Antibody

  • WB - PIK3C3 Antibody ASC11822
    Western blot analysis of PIK3C3 in mouse small intestine tissue lysate with PIK3C3 antibody at 1 µg/ml.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q8NEB9
Other Accession NP_002638, 34761064
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype IgG
Calculated MW Predicted: 91, 98 kDa

Observed: 98 kDa
Application Notes PIK3C3 antibody can be used for detection of PIK3C3 by Western blot at 1 - 2 µg/ml.
Additional Information
Gene ID 5289
Target/Specificity PIK3C3; PIK3C3 antibody is human, mouse and rat reactive.
Reconstitution & Storage PIK3C3 antibody can be stored at 4℃ for three months and -20℃, stable for up to one year.
PrecautionsPIK3C3 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name PIK3C3
Synonyms VPS34
Function Catalytic subunit of the PI3K complex that mediates formation of phosphatidylinositol 3-phosphate which plays a key role in initiation and maturation of autophagosomes. Involved in the transport of lysosomal enzyme precursors to lysosomes. Required for the abcission step in cytokinesis. Required for transport from early to late endosomes.
Cellular Location Midbody. Late endosome. Note=Localizes also to discrete punctae along the ciliary axoneme and to the base of the ciliary axoneme.
Tissue Location Ubiquitously expressed, with a highest expression in skeletal muscle.
Research Areas
Citations (0)

Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.

Submit your citation using an Abgent antibody to, and receive a free "I Love Antibodies" mug.


PI 3-kinase p100 (phosphoinositide-3-kinase p100 subunit), also known as hVps34 or PIK3C3 (phosphoinositide-3-kinase class III), is a member of the PI3/PI4-kinase family (1). It is a catalytic subunit of the PI3K complex that mediates formation of phosphatidylinositol 3-phosphate and ubiquitously expressed with a highest expression in skeletal muscle (1,2). PIK3C3 is involved in the endosome to lysosome transport and plays important roles in intracellular membrane trafficking and autophagy (3-5).


Stopkova P, Saito T, Papolos DF, et al. Identification of PIK3C3 promoter variant associated with bipolar disorder and schizophrenia. Biol. Psychiatry 2004; 55:981-8.
Hal BS, Gabernet-Castello C, Voak A, et al. TbVps34, the trypanosome orthologue of Vps34, is required for Golgi complex segregation. J. Biol. Chem. 2006; 281:27600-12.
Backer JM. The regulation and function of class III PI3Ks: novel roles for Vps34. Biochem. J. 2008; 410:1-17.
Jaber N, Dou Z, Lin RZ, et al. Mammalian PIK3C3/VPS34: the key to autophagic processing in liver and heart. Autophagy 2012; 8:707-8.

Abgent welcomes feedback from its customers.

If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.

If you have any additional inquiries please email technical services at

$ 310.00
Cat# ASC11822
(40 western blots)
Availability: 5-7days
Bulk Size
Seasonal Special on Bulk Order
Request Quote Here

Ordering Information

United States
AlbaniaAustraliaAustriaBelgiumBosnia & HerzegovinaBrazilBulgariaCanadaChinaCroatiaCyprusCzech RepublicDenmarkEstoniaFinlandFranceGermanyGreeceHong KongHungaryIcelandIndiaIndonesiaIrelandIsraelItalyJapanKoreaLatviaLithuaniaLuxembourgMacedoniaMalaysiaMaltaNetherlandsNew ZealandNorwayPakistanPolandPortugalRomaniaSerbiaSingaporeSlovakiaSloveniaSouth AfricaSpainSwedenSwitzerlandTaiwanTurkeyUnited KingdomUnited StatesVietnamOthers
Abgent, Inc.
(888) 735-7227 / (858) 622-0099
(858) 622-0609

Shipping Information

Domestic orders (in stock items)
Shipped out the same day. Orders placed after 1 PM (PST) will ship out the next business day.
International orders
Contact your local distributors
Santa Cruz Alternative
Terms & Conditions