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SOX18 Antibody

  • WB - SOX18 Antibody ASC11831
    Western blot analysis of SOX18 in 3T3 cell lysate with SOX18 antibody at 1 µg/ml.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P35713
Other Accession NP_060889, 8924248
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype IgG
Calculated MW Predicted: 42 kDa

Observed: 44 kDa
Application Notes SOX18 antibody can be used for detection of SOX18 by Western blot at 1 - 2 µg/ml.
Additional Information
Gene ID 54345
Target/Specificity SOX18; SOX18 antibody is human, mouse and rat reactive. SOX18 is predicted to not cross-react with other SOX proteins.
Reconstitution & Storage SOX18 antibody can be stored at 4℃ for three months and -20℃, stable for up to one year.
PrecautionsSOX18 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name SOX18
Function Binds to the consensus sequence 5'-AACAAAG-3' and is able to trans-activate transcription via this site.
Cellular Location Nucleus {ECO:0000255|PROSITE- ProRule:PRU00267}
Citations (0)

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SOX18 is a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate (1,2). SOX18 is part of the SoxF subgroup which plays an important role in the differentiation of different cell types (3). SOX is known to be involved with vascularization and endothelial development, suggesting that it may be useful as a potential target for inhibiting tumor angiogenesis (4). Mutations in this gene have been associated with recessive and dominant forms of hypotrichosis-lymphedema-telangiectasia (5).


Dunn TL, Mynett-Johnson L, Wright EM, et al. Sequence and expression of Sox-18 encoding another HMG-box transcription factor. Gene 1995; 161:223-5.
Jiang T, Hou CC, She ZY, et al. The SOX gene family: function and regulation in testis determination and male fertility maintenance. Mol. Biol. Rep. 2013; 40:2187-94.
Francois M, Koopman P, and Beltrame M. SoxF genes: key players in the development of the cardiovascular system. Int. J. Biochem. Cell Biol. 2010; 42:445-8.
Young N, Hahn CN, Poh A, et al. Effect of disrupted SOX18 transcription factor function on tumor growth, vascularization, and endothelial development. J. Natl. Cancer Inst. 2006; 98:1060-7.

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$ 310.00
Cat# ASC11831
(40 western blots)
Availability: 5-7days
Bulk Size
Seasonal Special on Bulk Order
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