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BATF3 Antibody

  • WB - BATF3 Antibody ASC11841
    Western blot analysis of BATF3 in 293 cell lysate with BATF3 antibody at 1 µg/ml in (A) the absence and (B) the presence of blocking peptide.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9NR55
Other Accession NP_061134, 8924246
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype IgG
Calculated MW Predicted: 14 kDa

Observed: 17 kDa
Application Notes BATF3 body can be used for detection of BATF3 by Western blot at 1 - 2 µg/ml.
Additional Information
Gene ID 55509
Target/Specificity BATF3; BATF3 antibody is human, mouse and rat reactive. BATF3 antibody is predicted to have no cross-reactivity to other BATF family members.
Reconstitution & Storage BATF3 antibody can be stored at 4℃ for three months and -20℃, stable for up to one year.
PrecautionsBATF3 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name BATF3
Synonyms SNFT
Function AP-1 family transcription factor that controls the differentiation of CD8(+) thymic conventional dendritic cells in the immune system. Required for development of CD8-alpha(+) classical dendritic cells (cDCs) and related CD103(+) dendritic cells that cross-present antigens to CD8 T-cells and produce interleukin-12 (IL12) in response to pathogens (By similarity). Acts via the formation of a heterodimer with JUN family proteins that recognizes and binds DNA sequence 5'-TGA[CG]TCA-3' and regulates expression of target genes.
Cellular Location Nucleus {ECO:0000255|PROSITE- ProRule:PRU00978, ECO:0000269|PubMed:12087103}
Citations (0)

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BATF3, also known as SNFT, belongs to the basic leucine zipper transcriptional family and functions as a transcriptional repressor when heterodimerizing with Jun (1) and can repress the transcription of IL-2 and MMP-1 (1,2). BATF3 is required for the development of CD8alpha+ classical dendritic cells (DCs) and the related CD103+ DCs that cross-present antigens to CD8 T cells (3,4).


Iacobelli M, Wachsman W, and McGuire KL. Repression of IL-2 promoter activity by the novel basic leucine zipper p21SNFT protein. J. Immunol. 2000; 154:860-8.
Bower KE, Fritz JM, and McGuire KL. Transcriptional repression of MMP-1 by p21SNFT and reduced invasiveness of hepatocarcinoma cells. Oncogene 2004; 23:8805-14.
Hildner K, Edelson BT, Purtha WE, et al. BATF3 deficiency reveals a critical role for CD8alpha+ dendritic cells in cytotoxic T cell immunity. Science 2008; 322:1097-1100.
Edelson BT, Peripheral CD103+ dendritic cells form a unified subset developmentally related to CD8alpha+ conventional dendritic cells. J. Exp. Med. 2010; 207:823-36.

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$ 310.00
Cat# ASC11841
(40 western blots)
Availability: 5-7days
Bulk Size
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