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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   RHOG Antibody   

RHOG Antibody

  • WB - RHOG Antibody ASC11858
    Western blot analysis of RHOG in human kidney tissue lysate with RHOG antibody at 1 µg/ml.
  • IHC - RHOG Antibody ASC11858
    Immunohistochemistry of RHOG in mouse kidney tissue with RHOG antibody at 5 µg/ml.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P84095
Other Accession NP_001656, 46249393
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype IgG
Calculated MW Predicted: 21 kDa

Observed: 23 kDa
Application Notes RHOG antibody can be used for detection of RHOG by Western blot at 1 - 2 µg/ml. Antibody can also be used for immunohistochemistry starting at 5 µg/mL.
Additional Information
Gene ID 391
Target/Specificity RHOG; RHOG antibody is human, mouse and rat reactive.
Reconstitution & Storage RHOG antibody can be stored at 4℃ for three months and -20℃, stable for up to one year.
PrecautionsRHOG Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms ARHG
Function Required for the formation of membrane ruffles during macropinocytosis. Plays a role in cell migration and is required for the formation of cup-like structures during trans-endothelial migration of leukocytes. In case of Salmonella enterica infection, activated by SopB and ARHGEF26/SGEF, which induces cytoskeleton rearrangements and promotes bacterial entry.
Cellular Location Cell membrane; Lipid-anchor; Cytoplasmic side
Research Areas
Citations (0)

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The ras homolog family member G (RHOG), also known as rho-related GTP-binding protein, is a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades (1). RHOG controls a pathway that requires the microtubule network and activates Rac1 and Cdc42Hs independently of their growth factor signaling pathway (2). RHOG is also involved in the transcriptional regulation of interferon-gamma and nuclear factor of activated T cells (NFAT) and the regulation of the actin skeleton in lymphocytes (3).


Vincent S, Janteur P, and Fort P. Growth-regulated of rhoG, a new member of the ras homolog family. Mol. Cell Biol. 1992; 12:3138-48.
Gauthier-Rouviere C, Vignal E, Meriane M, et al. RhoG GTPase controls a pathway that independently activates Rac1 and Cdc42Hs. Mol. Biol. Cell 1998; 9:1379-94.
Vigorito E, Billadeu DD, Savoy D, et al. RhoG regulates gene expression and the actin skeleton in lymphocytes. Oncogene 2003; 22:330-42.

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$ 310.00
Cat# ASC11858
(40 western blots)
Availability: 5-7days
Bulk Size
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