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>   home   >   Products   >   Primary Antibodies   >   Neuroscience   >   FOXG1 Antibody   

FOXG1 Antibody

  • WB - FOXG1 Antibody ASC11891
    Western blot analysis of FOXG1 in rat brain tissue lysate with FOXG1 antibody at 1 µg/ml.
  • IF - FOXG1 Antibody ASC11891
    Immunofluorescence of FOXG1 in mouse brain tissue with FOXG1 antibody at 20 µg/ml.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P55316
Other Accession NP_005240, 32307177
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype IgG
Calculated MW Predicted: 54 kDa

Observed: 54 kDa
Application Notes FOXG1 antibody can be used for detection of FOXG1 by Western blot at 1 - 2 µg/ml. For immunofluorescence start at 20 µg/mL.
Additional Information
Gene ID 2290
Target/Specificity FOXG1; FOXG1 antibody is human, mouse and rat reactive.
Reconstitution & Storage FOXG1 antibody can be stored at 4℃ for three months and -20℃, stable for up to one year.
PrecautionsFOXG1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name FOXG1
Function Transcription repression factor which plays an important role in the establishment of the regional subdivision of the developing brain and in the development of the telencephalon.
Cellular Location Nucleus {ECO:0000255|PROSITE- ProRule:PRU00089, ECO:0000269|PubMed:21280142}
Tissue Location Expression is restricted to the neurons of the developing telencephalon.
Research Areas
Citations (0)

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FOXG1 belongs to the forkhead family of transcription factors which is characterized by a distinct forkhead domain and plays an important role in the development of the brain and telencephalon (1). It is essential for the proliferation of progenitor cells in the cerebral cortex and influences regional patterning in the mammalian telencephalon (2,3). Expression is restricted to the neurons of the developing telencephalon (3). The loss of FOXG1 results in an accelerated rate of neuronal differentiation and the shortening of the neurogenetic period in the embryonic cerebral cortex (2,4).


Murphy DB, Wiese S, Burfeind P, et al. Human brain factor 1, a new member of the fork head gene family. Genomics 1994; 21:551-7.
Kumamoto T, Toma K, Gunadi, et al. Foxg1 coordinates the switch from nonradially to radially migrating glutamatergic subtypes in the neocortex through spatiotemporal repression. Cell Rep. 2013; 3:931-45.
Miyoshi G and Fishell G. Dynamic FoxG1 expression coordinates the integration of multipolar pyramidal neuron precursors into the cortical plate. Neuron 2012;74:1045-58.
Mencarelli MA, Spanhol-Rosseto A, Artuso R, et al. Novel FOXG1 mutations associated with the congenital variant of Rett syndrome. J. Med. Genet. 2010; 47:49-53.

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$ 310.00
Cat# ASC11891
(40 western blots)
Availability: 5-7days
Bulk Size
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