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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   SLC29A2 Antibody   

SLC29A2 Antibody

  • WB - SLC29A2 Antibody ASC11904
    Western blot analysis of SLC29A2 in human bladder tissue lysate with SLC29A2 antibody at 1 µg/ml.
  • IHC - SLC29A2 Antibody ASC11904
    Immunohistochemistry of SLC29A2 in human bladder tissue with SLC29A2 antibody at 2.5 µg/mL.
  • IF - SLC29A2 Antibody ASC11904
    Immunofluorescence of SLC29A2 in human bladder tissue with SLC29A2 antibody at 20 µg/ml.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q14542
Other Accession NP_001523, 38708299
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype IgG
Calculated MW Predicted: 50 kDa; Observed: 50 kDa
Application Notes SLC29A2 antibody can be used for detection of SLC29A2 by Western blot at 1 - 2 µg/ml. Antibody can also be used for immunohistochemistry starting at 2.5 µg/mL. For immunofluorescence start at 20 µg/mL.
Additional Information
Gene ID 3177
Target/Specificity SLC29A2; SLC29A2 antibody is human specific. SLC29A2 antibody is predicted to not cross-react with other SLC29 proteins.
Reconstitution & Storage SLC29A2 antibody can be stored at 4℃ for three months and -20℃, stable for up to one year.
PrecautionsSLC29A2 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name SLC29A2
Synonyms DER12, ENT2, HNP36
Function Mediates equilibrative transport of purine, pyrimidine nucleosides and the purine base hypoxanthine. Very less sensitive than SLC29A1 to inhibition by nitrobenzylthioinosine (NBMPR), dipyridamole, dilazep and draflazine.
Cellular Location Basolateral cell membrane; Multi-pass membrane protein. Nucleus membrane; Multi-pass membrane protein. Note=Localized at the basolateral cell membrane in polarized MDCK cells
Tissue Location Expressed in skeletal muscle, liver, lung, placenta, brain, heart, kidney and ovarian tissues
Research Areas
Citations (0)

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SLC29A2 is a member of the equilibrative nucleoside transporter family which plays a key role in nucleoside and nucleobase uptake for salvage pathways of nucleotide synthesis (1,2). SLC29A2 is a transmembrane glycoprotein that mediates the cellular uptake of nucleosides from the surrounding medium (3). As a nucleoside transporter, SLC29A2 plays an important role in the uptake of nucleoside-based anti-cancer drugs; polymorphisms of point mutations in the gene encoding this protein may affect the efficacy of these drugs (4).


Williams JB and Lanahan AA. A mammalian delayed-early response gene encodes HNP36, a novel, conserved nucleolar protein. Biochim. Biophys. Res. Commun. 1995; 213:325-33.
Young JD, Yao SY, Baldwin JM, et al. The human concentrative and equilibrative nucleoside transporter families, SLC28 and SLC29. Mol. Aspects. Med. 34:529-47.
Mangravite LM, Xiao G, and Giacomini KM. Localization of human equilibrative nucleoside transporters, hENT1 and hENT2, in renal epithelial cells. Am. J. Physiol. Renal Physiol. 284:F902-10.
Owen RP, Lagpacan LL, Taylor TR, et al. Functional characterization and haplotype analysis of polymorphisms in the human equilabrative nucleoside transporter, ENT2. Drug Metab. Dispos. 2006; 34:12-5.

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$ 330.00
Cat# ASC11904
Availability: 5-7days
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