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NAP1L5 Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC-P, IF, E |
|---|---|
| Primary Accession | Q96NT1 |
| Other Accession | NP_715638, 24371268 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Calculated MW | Predicted: 20 kDa (17kDa in mouse) Observed: 15 kDa |
| Application Notes | NAP1L5 antibody can be used for detection of NAP1L5 by Western blot at 1 - 2 µg/mL. Antibody can also be used for immunohistochemistry starting at 5 µg/mL. For immunofluorescence start at 20 µg/mL. |
| Gene ID | 266812 |
|---|---|
| Target/Specificity | NAP1L5; NAP1L5 antibody is human, mouse and rat reactive. |
| Reconstitution & Storage | NAP1L5 antibody can be stored at 4℃ for three months and -20℃, stable for up to one year. |
| Precautions | NAP1L5 Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | NAP1L5 |
|---|---|
| Synonyms | DRLM |
| Cellular Location | Nucleus. |
| Tissue Location | Predominantly expressed in brain. |
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Provided below are standard protocols that you may find useful for product applications.
Background
The nucleosome assembly protein 1-like 5 (NAP1L5) protein, also known as DRLM, was initially identified as a possible tumor suppressor gene in hepatocellular carcinoma (1). The NAP1L5 gene is located within the intron of Herc3, and unlike Herc3, is imprinted and highly expressed in regions of the adult mouse brain (2).
References
Harada H, Nagai H, Ezura Y, et al. Down-regulation of a novel gene, DRLM, in human liver malignancy from 4q22 that encodes a NAP-like protein. Gene 2002; 296:171-7.
Davies W, Smith RJ, Kelsey G, et al. Expression patterns of the novel imprinted genes Nap1L5 and Peg13 and their non-imprinted host genes in the adult mouse brain. Gene Expr. Patterns 2004; 4:741-7.
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