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MEK1/2 Antibody

  • WB - MEK1/2 Antibody ASC11934
    Western blot analysis of MEK1/2 in human brain tissue lysate with MEK1/2 antibody at 1 µg/ml in (A) the absence and (B) the presence of blocking peptide.
  • IHC - MEK1/2 Antibody ASC11934
    Immunohistochemistry of MEK1/2 in mouse brain tissue with MEK1/2 antibody at 5 µg/mL.
  • IF - MEK1/2 Antibody ASC11934
    Immunofluorescence of MEK1/2 in mouse brain tissue with MEK1/2 antibody at 20 µg/mL.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q0VD16
Other Accession NP_002746, 5579478
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype IgG
Calculated MW Predicted: 43 kDa; Observed: 44 kDa
Application Notes MEK1/2 antibody can be used for detection of MEK1/2 by Western blot at 1 - 2 µg/ml. Antibody can also be used for immunohistochemistry starting at 5 µg/mL. For immunofluorescence start at 20 µg/mL.
Additional Information
Gene ID 5604
Target/Specificity MAP2K1; MEK1/2 antibody is human, mouse, and rat reactive. This antibody detects both MEK1 and MEK2.
Reconstitution & Storage MEK1/2 antibody can be stored at 4℃ for three months and -20℃, stable for up to one year.
PrecautionsMEK1/2 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Citations (0)

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The mitogen-activated protein kinase kinase 1 (MAP2K1, also known as MEK1) and the highly homologous MEK2 are members of the dual specificity protein kinase family (1). MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals (2). MEK1 lies upstream of MAP kinases and stimulates the enzymatic activity of MAP kinases upon wide variety of extra- and intracellular signals. As an essential component of MAP kinase signal transduction pathway, MEK1 is involved in many cellular processes such as proliferation, differentiation, transcription regulation and development (2).


Zheng CF and Guan KL. Cloning and characterization of two distinct human extracellular signal-regulated kinase activator kinases, MEK1 and MEK2. J. Biol. Chem. 1993; 268:11435-9.
Marais R and Marshall CJ. Control of the ERK MAP kinase cascade by Ras and Raf. Cancer Surv. 1996; 27:101-25.

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$ 310.00
Cat# ASC11934
(40 western blots)
Availability: 5-7days
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