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>   home   >   Products   >   Primary Antibodies   >   C18orf42 Antibody   

C18orf42 Antibody

     
  • IF - C18orf42 Antibody ASC11968
    Immunofluorescence of SRSF3 in K562 cells with SRSF3 antibody at 2 µg/mL.
  • IHC - C18orf42 Antibody ASC11968
    Immunohistochemistry of Rheb in mouse brain tissue with Rheb antibody at 5 µg/ml.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IF, ICC, E
Primary Accession P0CW23
Other Accession NP_001138666, 642597
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype IgG
Calculated MW Predicted: 8 kDa

Observed: 12 kDa
Application Notes C18orf42 antibody can be used for the detection of C18orf42 by Western blot at 1 - 2 μg/mL. Antibody can also be used for Immunocytochemistry starting at 2 μg/mL. For immunofluorescence start at 2 μg/mL.
Additional Information
Gene ID 642597
Target/Specificity C18orf42 antibody was raised against a 16 amino acid peptide from near the center of human C18orf42.

The immunogen is located within the last 50 amino acids of C18orf42.
Reconstitution & Storage C18orf42 antibody can be stored at 4℃ for three months and -20℃, stable for up to one year.
PrecautionsC18orf42 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name AKAIN1 (HGNC:28285)
Synonyms C18orf42
Function Protein kinase A (PKA)-binding protein. Binds to type II regulatory subunits of protein kinase A (PKA) and may block the A- kinase anchoring protein (AKAP)-mediated subcellular localization of PKA (PubMed:25653177).
Tissue Location Preferentially expressed in the neural tissues (PubMed:25653177).
Citations (0)

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Background

Little is known of the function of the protein encoded by Chromosome 18 open reading frame 18 (C18orf42), but it is preferentially expressed in neuronal tissue (1). It is thought to bind to the cAMP-dependent protein kinase A (PKA) and regulation its interaction with members of the A-kinase anchoring protein (AKAP) family (1).

References

Fukuda M and Aizawa Y. Hypothetical gene C18orf42 encodes a novel protein kinase A-binding protein. Genes Cells 2015; 20:267-80.


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$ 330.00
Cat# ASC11968
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