Slo2.2 Antibody
Slo2.2 Antibody, Clone S3-26
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC, ICC/IF, AM |
---|---|
Primary Accession | Q9Z258 |
Other Accession | NP_068625 |
Host | Mouse |
Isotype | IgG1 |
Reactivity | Human, Mouse, Rat |
Clonality | Monoclonal |
Description | Mouse Anti-Rat Slo2.2 Monoclonal IgG1 |
Target/Specificity | Detects ~140kDa. Weak human detection. |
Other Names | KCNT1 Antibody, potassium channel subfamily T member 1 Antibody, bA100C15.2 Antibody, SLACK Antibody, KCa4.1KIAA1422FLJ41282 Antibody |
Clone Names | S3-26 |
Immunogen | Fusion protein amino acids 1168-1237 of rat Slo2.2 (Slack) |
Purification | Protein G Purified |
Storage | -20ºC |
Storage Buffer | PBS pH7.4, 50% glycerol, 0.09% sodium azide |
Shipping Temperature | Blue Ice or 4ºC |
Certificate of Analysis | 1 µg/ml of SMC-323 was sufficient for detection of Slo2.2 in 10 µg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody. |
Cellular Localization | Cell Membrane |
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Provided below are standard protocols that you may find useful for product applications.
Background
Slo2.2 is a novel member of the mammalian Slo potassium channel gene family. Slo2 channels may contribute to the resting potentials of cells that control their basal level of excitability (1). They also have sensors that couple channel activity to the intracellular concentrations of Na+ and Cl- (2).
References
1. Santi C.M., et al. (2006) J Neuroscience, 26(19): 5059-5068.
2. Yuan A., et al. (2003) Neuron 37: 765-773.
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