GABA-A Receptor Delta Antibody
GABA A Receptor Delta Antibody, Clone S151-3
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, ICC, AM |
---|---|
Primary Accession | P18506 |
Other Accession | NP_058985.1 |
Host | Mouse |
Isotype | IgG2a |
Reactivity | Human, Mouse, Rat |
Clonality | Monoclonal |
Description | Mouse Anti-Rat GABA-A Receptor Delta Monoclonal IgG2a |
Target/Specificity | Detects ~55kDa. |
Other Names | GABAA-RD Antibody, Gabrd Antibody, MGC105467 Antibody |
Clone Names | S151-3 |
Immunogen | Synthetic peptide amino acids 15-34 of rat GABA-A-R-Delta |
Purification | Protein G Purified |
Storage | -20ºC |
Storage Buffer | PBS pH7.4, 50% glycerol, 0.09% sodium azide |
Shipping Temperature | Blue Ice or 4ºC |
Certificate of Analysis | 2 µg/ml of SMC-345 was sufficient for detection of Delta1 GABA-A receptor in 10 µg of rat brain lysate by colorimetric immunoblot analysis using goat anti-mouse IgG:HRP as the secondary antibody. |
Cellular Localization | Cell Membrane | Cell Junction | Synapse | Postsynaptic Cell Membrane |
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Provided below are standard protocols that you may find useful for product applications.
Background
The GABA-A receptor is a member of the superfamily of fast acting ligand-gated ion channels. The individual subunits of these receptors have similar sequences and structural features (1). GABA-A receptors are the major fast inhibitory neurotransmitter gated ion channels in the brain (2).
References
1. Bracamontes J.R. and Steinbach J.H. (2008) J Bio Chem. 283: 26128-26136.
2. Macdonald R.L., Olsen R.W. (1993) Annu Rev Neurosci. 17: 569-602.
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