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Ankyrin G Antibody
Ankyrin G Antibody, Clone S106-20
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, ICC |
|---|---|
| Primary Accession | Q12955 |
| Other Accession | NP_066267.2 |
| Host | Mouse |
| Isotype | IgG1 |
| Reactivity | Human, Mouse, Rat |
| Clonality | Monoclonal |
| Description | Mouse Anti-Human Ankyrin G Monoclonal IgG1 |
| Target/Specificity | Detects >~200kDa. |
| Other Names | ANK-3 Antibody, ANK3 Antibody, ankyrin 3 Antibody, Ankryin G119 Antibody, brain specific ankyrin G Antibody, CHANK3 Antibody, ankyrin 3 (G) Antibody, Ankyrin-3 Antibody, Ankyrin-G Antibody, node of Ranvier (ankyrin G) Antibody, Ankyrin 3 Antibody, node of Ranvier Antibody, Ankyrin G119 Antibody, FLJ45464 Antibody, OTTHUMP00000217458 Antibody, OTTHUMP00000217575 Antibody, RP11 369L1.1 Antibody |
| Clone Names | S106-20 |
| Immunogen | Fusion protein 1000 C-terminal amino acids of human Ankyrin G encompassing all of Ankyrin G with the exception of Ankyrin repeats |
| Purification | Protein G Purified |
| Storage | -20ºC |
| Storage Buffer | PBS pH7.4, 50% glycerol, 0.09% sodium azide |
| Shipping Temperature | Blue Ice or 4ºC |
| Certificate of Analysis | 1 µg/ml of SMC-404 was sufficient for detection of Ankyrin-G in 20 µg of rat brain membrane lysate and assayed by colorimetric immunoblot analysis using goat anti-mouse IgG:HRP as the secondary antibody. |
| Cellular Localization | Cytoplasm | Cytoskeleton | Cell Projection | Axon | Cell Membrane | Sarcolemma | Cell Junction | Synapse | Postsynaptic Cell Membrane | Lysosome |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Ankyrins are a family of adaptor proteins that mediate the attachment of integral membrane proteins to the spectrin-actin based membrane skeleton (1). Ankyrins have binding sites for the beta subunit of spectrin and at least 12 families of integral membrane proteins. This linkage is required to maintain the integrity of the plasma membranes and to anchor specific ion channels, ion exchangers and ion transporters in the plasma membrane.
References
1. Bennett V., Baines A.J. (2001) Physiol. Rev. 81 (3): 1353–92.
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