PEX6 Antibody
PEX6 Antibody, Clone S233-8
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, ICC/IF |
---|---|
Primary Accession | Q13608 |
Other Accession | NP_000278.3 |
Host | Mouse |
Isotype | IgG1 |
Reactivity | Human, Rat |
Clonality | Monoclonal |
Description | Mouse Anti-Human PEX6 Monoclonal IgG1 |
Target/Specificity | Detects ~100kDa. |
Other Names | PAF 2 Antibody, Peroxin 6 Antibody, Peroxisomal AAA type ATPase 1 Antibody, Peroxisomal biogenesis factor 6 Antibody, PXAAA1 Antibody, peroxisomal-type ATPase 1 Antibody, peroxisome biogenesis factor 6 Antibody |
Clone Names | S233-8 |
Immunogen | Fusion protein amino acids 2-294 (N-terminus) of human PEX6. Rat: 82% identity (243/293 amino acids identical). Mouse: 82% identity (244/294 amino acids identical). <50% identity with other PEX proteins. |
Purification | Protein G Purified |
Storage | -20ºC |
Storage Buffer | PBS pH 7.4, 50% glycerol, 0.1% sodium azide |
Shipping Temperature | Blue Ice or 4ºC |
Certificate of Analysis | 1 µg/ml of SMC-470 was sufficient for detection of PEX6 in 20 µg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody. |
Cellular Localization | Cytoplasm | Peroxisome | Peroxisome Membrane |
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes a member of the AAA (ATPases associated with diverse cellular activities) family of ATPases. This member is a predominantly cytoplasmic protein, which plays a direct role in peroxisomal protein import and is required for PTS1 (peroxisomal targeting signal 1, a C-terminal tripeptide of the sequence ser-lys-leu) receptor activity. Mutations in this gene cause peroxisome biogenesis disorders of complementation group 4 and complementation group 6.
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