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ABHD5 Antibody (monoclonal) (M02)

Mouse monoclonal antibody raised against a partial recombinant ABHD5.

     
  • WB - ABHD5 Antibody (monoclonal) (M02) AT1013a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (37.07 KDa) .
    detail
  • WB - ABHD5 Antibody (monoclonal) (M02) AT1013a
    ABHD5 monoclonal antibody (M02), clone 4B12 Western Blot analysis of ABHD5 expression in A-431 ( (Cat # AT1013a )
    detail
  • E - ABHD5 Antibody (monoclonal) (M02) AT1013a
    Detection limit for recombinant GST tagged ABHD5 is 0.3 ng/ml as a capture antibody.
    detail
  • SPECIFICATION
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession Q8WTS1
Other Accession NM_016006
Reactivity Human
Host mouse
Clonality Monoclonal
Isotype IgG1 Kappa
Clone Names 4B12
Calculated MW 39096 Da
Additional Information
Gene ID 51099
Other Names 1-acylglycerol-3-phosphate O-acyltransferase ABHD5, Abhydrolase domain-containing protein 5, Lipid droplet-binding protein CGI-58, ABHD5, NCIE2
Target/Specificity ABHD5 (NP_057090, 240 a.a. ~ 342 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsABHD5 Antibody (monoclonal) (M02) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)
citation

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Background

The protein encoded by this gene belongs to a large family of proteins defined by an alpha/beta hydrolase fold, and contains three sequence motifs that correspond to a catalytic triad found in the esterase/lipase/thioesterase subfamily. It differs from other members of this subfamily in that its putative catalytic triad contains an asparagine instead of the serine residue. Mutations in this gene have been associated with Chanarin-Dorfman syndrome, a triglyceride storage disease with impaired long-chain fatty acid oxidation.

References

1.The Cannabinoid Receptor Agonist THC Attenuates Weight Loss in a Rodent Model of Activity-Based Anorexia.Verty AN, Evetts MJ, Crouch GJ, McGregor IS, Stefanidis A, Oldfield BJ.Neuropsychopharmacology. 2011 Jun;36(7):1349-58. Epub 2011 Mar 16.2.Adipose triacylglycerol lipase deletion alters whole body energy metabolism and impairs exercise performance in mice.Huijsman E, van de Par C, Economou C, van der Poel C, Lynch GS, Schoiswohl G, Haemmerle G, Zechner R, Watt MJ.Am J Physiol Endocrinol Metab. 2009 Aug;297(2):E505-13. Epub 2009 Jun 2.3.Adipose Triglyceride Lipase Regulation of Skeletal Muscle Lipid Metabolism and Insulin Responsiveness.Watt MJ, van Denderen BJ, Castelli LA, Bruce CR, Hoy AJ, Kraegen EW, Macaulay L, Kemp BE.Mol Endocrinol. 2008 May;22(5):1200-12. Epub 2008 Jan 17.

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$ 350.00
Cat# AT1013a
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Availability: 7-10 days
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