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ABTB1 Antibody (monoclonal) (M01)Purified Mouse Monoclonal Antibody (Mab)
| Country | United States
Ordering Information
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| Catalog # | Size | Availability | Price | |
| AT1015a | 100 ug 400 ul | 7-10 days | $ 315.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
- Specification
- Citiations : 0
- Reviews
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- Backgrounds
ABTB1 Antibody (monoclonal) (M01) - Product info | |
| Primary Accession | Q969K4 |
| Other Accession | NP_742024 |
| Reactivity | Human |
| Isotype | IgG2a Kappa |
| Clone Names | 3B3 |
| Calculated MW | 53979 Da |
ABTB1 Antibody (monoclonal) (M01) - Additional info | |
| Gene ID 80325 | |
| Other Names BPOZ, EF1ABP, MGC20585, PP2259ankyrin repeat and BTB (POZ) domain containing 1 | |
| Target/Specificity ABTB1 (NP_742024, 271 a.a. ~ 371 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. | |
| Format Clear, colorless solution in phosphate buffered saline, pH 7.2 . | |
| Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. | |
| Precautions ABTB1 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures. | |
ABTB1 Antibody (monoclonal) (M01) - Related products
ABTB1 Antibody (monoclonal) (M01) - Application data
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Detection limit for recombinant GST tagged ABTB1 is approximately 0.03ng/ml as a capture antibody.
ABTB1 Antibody (monoclonal) (M01) - Research Areas
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BACKGROUND
This gene encodes a protein with an ankyrin repeat region and two BTB/POZ domains, which are thought to be involved in protein-protein interactions. Expression of this gene is activated by the phosphatase and tensin homolog, a tumor suppressor. Alternate splicing results in three transcript variants.
REFERENCES
BPOZ-2 directly binds to eEF1A1 to promote eEF1A1 ubiquitylation and degradation and prevent translation. Koiwai K, et al. Genes Cells, 2008 Jun. PMID 18459963.Bood POZ containing gene type 2 is a human counterpart of yeast Btb3p and promotes the degradation of terminal deoxynucleotidyltransferase. Maezawa S, et al. Genes Cells, 2008 May. PMID 18429817.Large-scale cDNA transfection screening for genes related to cancer development and progression. Wan D, et al. Proc Natl Acad Sci U S A, 2004 Nov 2. PMID 15498874.The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334.Functional proteomics mapping of a human signaling pathway. Colland F, et al. Genome Res, 2004 Jul. PMID 15231748.
