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ACP2 Antibody (monoclonal) (M01)

Mouse monoclonal antibody raised against a full length recombinant ACP2.

     
  • IF - ACP2 Antibody (monoclonal) (M01) AT1028a
    Immunofluorescence of monoclonal antibody to ACP2 on HeLa cell. [antibody concentration 10 ug/ml]
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  • WB - ACP2 Antibody (monoclonal) (M01) AT1028a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (72.27 KDa) .
    detail
  • WB - ACP2 Antibody (monoclonal) (M01) AT1028a
    Western Blot analysis of ACP2 expression in transfected 293T cell line by ACP2 monoclonal antibody (M01), clone M1-4A12.

    Lane 1: ACP2 transfected lysate(48.3 KDa).
    Lane 2: Non-transfected lysate.
    detail
  • WB - ACP2 Antibody (monoclonal) (M01) AT1028a
    Western blot analysis of ACP2 over-expressed 293 cell line, cotransfected with ACP2 Validated Chimera RNAi ( (Cat # AT1028a )
    detail
  • IHC - ACP2 Antibody (monoclonal) (M01) AT1028a
    Immunoperoxidase of monoclonal antibody to ACP2 on formalin-fixed paraffin-embedded human lymphoma tissue. [antibody concentration 5 ug/ml]
    detail
  • E - ACP2 Antibody (monoclonal) (M01) AT1028a
    Detection limit for recombinant GST tagged ACP2 is 1 ng/ml as a capture antibody.
    detail
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC, IF, E
Primary Accession P11117
Other Accession BC003160
Reactivity Human
Host mouse
Clonality Monoclonal
Isotype IgG2b lambda
Clone Names M1-4A12
Calculated MW 48344 Da
Additional Information
Gene ID 53
Other Names Lysosomal acid phosphatase, LAP, ACP2
Target/Specificity ACP2 (AAH03160, 1 a.a. ~ 423 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsACP2 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.
Citations (0)
citation

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Background

This gene encodes the beta subunit of lysosomal acid phosphatase (LAP). LAP is chemically and genetically distinct from red cell acid phosphatase. The encoded protein belongs to a family of distinct isoenzymes which hydrolyze orthophosphoric monoesters to alcohol and phosphate. Mutations in this gene or in the related alpha subunit gene cause acid phosphatase deficiency. Multiple alternatively spliced transcript variants encoding different isoforms have been identified for this gene.

References

Polymorphisms in mitochondrial genes and prostate cancer risk. Wang L, et al. Cancer Epidemiol Biomarkers Prev, 2008 Dec. PMID 19064571.Identification of a novel risk locus for progressive supranuclear palsy by a pooled genomewide scan of 500,288 single-nucleotide polymorphisms. Melquist S, et al. Am J Hum Genet, 2007 Apr. PMID 17357082.Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. Kimura K, et al. Genome Res, 2006 Jan. PMID 16344560.The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334.Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932.

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$ 350.00
Cat# AT1028a
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Availability: 7-10 days
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