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ADAM9 Antibody (monoclonal) (M01)Purified Mouse Monoclonal Antibody (Mab)
| Country | United States
Ordering Information
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| Catalog # | Size | Availability | Price | |
| AT1044a | 100 ug 400 ul | 7-10 days | $ 315.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
- Specification
- Citiations : 0
- Reviews
- Protocols
- Backgrounds
ADAM9 Antibody (monoclonal) (M01) - Product info | |
| Application | WB
|
| Primary Accession | Q13443 |
| Other Accession | NP_003807 |
| Reactivity | Human |
| Isotype | IgG1 Kappa |
| Clone Names | 3000000 |
| Calculated MW | 90556 Da |
ADAM9 Antibody (monoclonal) (M01) - Additional info | |
| Gene ID 8754 | |
| Other Names KIAA0021, MCMP, MDC9, Mltnga disintegrin and metalloproteinase domain 9 (meltrin gamma) | |
| Target/Specificity ADAM9 (NP_003807, 36 a.a. ~ 136 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. | |
| Dilution WB~~1:500~1000 | |
| Format Clear, colorless solution in phosphate buffered saline, pH 7.2 . | |
| Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. | |
| Precautions ADAM9 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures. | |
ADAM9 Antibody (monoclonal) (M01) - Related products
AP7437a: ADAM9 Antibody (N-term)
AP7437b: ADAM9 Antibody (C-term)
RI10115: ADAM9 predesign siRNA
BP7437a: ADAM9 Antibody (N-term) Blocking Peptide
ADAM9 Antibody (monoclonal) (M01) - Application data
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ADAM9 monoclonal antibody (M01), clone 3E6 Western Blot analysis of ADAM9 expression in A-431 ( Cat # L015V1 ).
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Detection limit for recombinant GST tagged ADAM9 is approximately 0.3ng/ml as a capture antibody.
ADAM9 Antibody (monoclonal) (M01) - Research Areas
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BACKGROUND
This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene interacts with SH3 domain-containing proteins, binds mitotic arrest deficient 2 beta protein, and is also involved in TPA-induced ectodomain shedding of membrane-anchored heparin-binding EGF-like growth factor. Several alternatively spliced transcript variants have been identified for this gene.
REFERENCES
RNAi-mediated ADAM9 gene silencing inhibits metastasis of adenoid cystic carcinoma cells. Xu Q, et al. Tumour Biol, 2010 Jun. PMID 20422344.Increased expression of a disintegrin and metalloprotease-9 in hepatocellular carcinoma: implications for tumor progression and prognosis. Tao K, et al. Jpn J Clin Oncol, 2010 Jul. PMID 20388695.Role of ADAMs in the ectodomain shedding and conformational conversion of the prion protein. Taylor DR, et al. J Biol Chem, 2009 Aug 21. PMID 19564338.Gene expression analysis of drug-resistant MCF-7 cells: implications for relation to extracellular matrix proteins. I?eri OD, et al. Cancer Chemother Pharmacol, 2010 Feb. PMID 19543729.Inhibition of platelets and tumor cell adhesion by the disintegrin domain of human ADAM9 to collagen I under dynamic flow conditions. Cominetti MR, et al. Biochimie, 2009 Aug. PMID 19505527.
