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ADAMTS2 Antibody (monoclonal) (M03)

Mouse monoclonal antibody raised against a partial recombinant ADAMTS2.

  • WB - ADAMTS2 Antibody (monoclonal) (M03) AT1049a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (36.63 KDa) .
  • WB - ADAMTS2 Antibody (monoclonal) (M03) AT1049a
    ADAMTS2 monoclonal antibody (M03), clone 7G3 Western Blot analysis of ADAMTS2 expression in PC-12 ( (Cat # AT1049a )
  • E - ADAMTS2 Antibody (monoclonal) (M03) AT1049a
    Detection limit for recombinant GST tagged ADAMTS2 is approximately 0.3ng/ml as a capture antibody.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O95450
Other Accession NM_014244
Reactivity Human, Rat
Host mouse
Clonality Monoclonal
Isotype IgG2a Kappa
Clone Names 7G3
Calculated MW 134755 Da
Additional Information
Gene ID 9509
Other Names A disintegrin and metalloproteinase with thrombospondin motifs 2, ADAM-TS 2, ADAM-TS2, ADAMTS-2, Procollagen I N-proteinase, PC I-NP, Procollagen I/II amino propeptide-processing enzyme, Procollagen N-endopeptidase, pNPI, ADAMTS2, PCINP, PCPNI
Target/Specificity ADAMTS2 (NP_055059, 1112 a.a. ~ 1210 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsADAMTS2 Antibody (monoclonal) (M03) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
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This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The enzyme encoded by this gene excises the N-propeptide of type I, type II and type V procollagens. Mutations in this gene cause Ehlers-Danlos syndrome type VIIC, a recessively inherited connective-tissue disorder. Alternative splicing results in multiple transcript variants.


ADAMTS-2 functions as anti-angiogenic and anti-tumoral molecule independently of its catalytic activity. Dubail J, et al. Cell Mol Life Sci, 2010 Jun 24. PMID 20574651.Genome-wide association scan of the time to onset of attention deficit hyperactivity disorder. Lasky-Su J, et al. Am J Med Genet B Neuropsychiatr Genet, 2008 Dec 5. PMID 18937294.Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. Kimura K, et al. Genome Res, 2006 Jan. PMID 16344560.Domains and maturation processes that regulate the activity of ADAMTS-2, a metalloproteinase cleaving the aminopropeptide of fibrillar procollagens types I-III and V. Colige A, et al. J Biol Chem, 2005 Oct 14. PMID 16046392.Novel types of mutation responsible for the dermatosparactic type of Ehlers-Danlos syndrome (Type VIIC) and common polymorphisms in the ADAMTS2 gene. Colige A, et al. J Invest Dermatol, 2004 Oct. PMID 15373769.

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$ 315.00
Cat# AT1049a
(40 western blots)
Availability: 7-10 days
Bulk Size
Seasonal Special on Bulk Order
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