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ADRA1A Antibody (monoclonal) (M01)

Mouse monoclonal antibody raised against a partial recombinant ADRA1A.

     
  • WB - ADRA1A Antibody (monoclonal) (M01) AT1058a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (28.71 KDa) .
    detail
  • WB - ADRA1A Antibody (monoclonal) (M01) AT1058a
    ADRA1A monoclonal antibody (M01), clone 4C7 Western Blot analysis of ADRA1A expression in HL-60 ( (Cat # AT1058a )
    detail
  • E - ADRA1A Antibody (monoclonal) (M01) AT1058a
    Detection limit for recombinant GST tagged ADRA1A is approximately 0.3ng/ml as a capture antibody.
    detail
  • SPECIFICATION
  • CITATIONS
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession P35348
Other Accession NM_033303
Reactivity Human
Host mouse
Clonality Monoclonal
Isotype IgG1 Kappa
Clone Names 4C7
Calculated MW 51487 Da
Additional Information
Gene ID 148
Other Names Alpha-1A adrenergic receptor, Alpha-1A adrenoreceptor, Alpha-1A adrenoceptor, Alpha-1C adrenergic receptor, Alpha-adrenergic receptor 1c, ADRA1A, ADRA1C
Target/Specificity ADRA1A (NP_150646, 1 a.a. ~ 27 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsADRA1A Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)
citation

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Background

Alpha-1-adrenergic receptors (alpha-1-ARs) are members of the G protein-coupled receptor superfamily. They activate mitogenic responses and regulate growth and proliferation of many cells. There are 3 alpha-1-AR subtypes: alpha-1A, -1B and -1D, all of which signal through the Gq/11 family of G-proteins and different subtypes show different patterns of activation. This gene encodes alpha-1A-adrenergic receptor. Alternative splicing of this gene generates four transcript variants, which encode four different isoforms with distinct C-termini but having similar ligand binding properties.

References

Association between Genetic Polymorphisms of Adrenergic Receptor and Diurnal Intraocular Pressure in Japanese Normal-Tension Glaucoma. Gao Y, et al. Ophthalmology, 2010 Aug 10. PMID 20705341.Variation at the NFATC2 Locus Increases the Risk of Thiazolinedinedione-Induced Edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) Study. Bailey SD, et al. Diabetes Care, 2010 Jul 13. PMID 20628086.Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. Rose JE, et al. Mol Med, 2010 Jul-Aug. PMID 20379614.Frequencies of polymorphisms in cytokines, neurotransmitters and adrenergic receptors in patients with complex regional pain syndrome type I after distal radial fracture. Herlyn P, et al. Clin J Pain, 2010 Mar-Apr. PMID 20173430.Lack of association between genetic polymorphisms affecting sympathetic activity and tilt-induced vasovagal syncope. Sorrentino S, et al. Auton Neurosci, 2010 Jun 24. PMID 20129829.

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$ 350.00
Cat# AT1058a
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Availability: 7-10 days
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