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ADRA1A Antibody (monoclonal) (M02)Purified Mouse Monoclonal Antibody (Mab)
| Country | United States
Ordering Information
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| Catalog # | Size | Availability | Price | |
| AT1059a | 100 ug 400 ul | 7-10 days | $ 315.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
- Specification
- Citiations : 0
- Reviews
- Protocols
- Backgrounds
ADRA1A Antibody (monoclonal) (M02) - Product info | |
| Application | WB
|
| Primary Accession | P35348 |
| Other Accession | NP_150646 |
| Reactivity | Human |
| Isotype | IgG1 Kappa |
| Clone Names | 5G8 |
| Calculated MW | 51487 Da |
ADRA1A Antibody (monoclonal) (M02) - Additional info | |
| Gene ID 148 | |
| Other Names ADRA1C, ADRA1L1, ALPHA1AARadrenergic, alpha-1A-, receptor | |
| Target/Specificity ADRA1A (NP_150646, 1 a.a. ~ 28 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. | |
| Dilution WB~~1:500~1000 | |
| Format Clear, colorless solution in phosphate buffered saline, pH 7.2 . | |
| Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. | |
| Precautions ADRA1A Antibody (monoclonal) (M02) is for research use only and not for use in diagnostic or therapeutic procedures. | |
ADRA1A Antibody (monoclonal) (M02) - Related products
RI10150: ADRA1A predesign siRNA
ADRA1A Antibody (monoclonal) (M02) - Application data
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ADRA1A monoclonal antibody (M02), clone 5G8. Western Blot analysis of ADRA1A expression in HL-60 ( Cat # L014V1 ).
ADRA1A Antibody (monoclonal) (M02) - Research Areas
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BACKGROUND
Alpha-1-adrenergic receptors (alpha-1-ARs) are members of the G protein-coupled receptor superfamily. They activate mitogenic responses and regulate growth and proliferation of many cells. There are 3 alpha-1-AR subtypes: alpha-1A, -1B and -1D, all of which signal through the Gq/11 family of G-proteins and different subtypes show different patterns of activation. This gene encodes alpha-1A-adrenergic receptor. Alternative splicing of this gene generates four transcript variants, which encode four different isoforms with distinct C-termini but having similar ligand binding properties.
REFERENCES
Association between Genetic Polymorphisms of Adrenergic Receptor and Diurnal Intraocular Pressure in Japanese Normal-Tension Glaucoma. Gao Y, et al. Ophthalmology, 2010 Aug 10. PMID 20705341.Variation at the NFATC2 Locus Increases the Risk of Thiazolinedinedione-Induced Edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) Study. Bailey SD, et al. Diabetes Care, 2010 Jul 13. PMID 20628086.Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. Rose JE, et al. Mol Med, 2010 Jul-Aug. PMID 20379614.Frequencies of polymorphisms in cytokines, neurotransmitters and adrenergic receptors in patients with complex regional pain syndrome type I after distal radial fracture. Herlyn P, et al. Clin J Pain, 2010 Mar-Apr. PMID 20173430.Lack of association between genetic polymorphisms affecting sympathetic activity and tilt-induced vasovagal syncope. Sorrentino S, et al. Auton Neurosci, 2010 Jun 24. PMID 20129829.
