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AHR Antibody (monoclonal) (M03)Purified Mouse Monoclonal Antibody (Mab)
| Country | United States
Ordering Information
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| Catalog # | Size | Availability | Price | |
| AT1074a | 100 ug 400 ul | 7-10 days | $ 315.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
- Specification
- Citiations : 0
- Reviews
- Protocols
- Backgrounds
AHR Antibody (monoclonal) (M03) - Product info | |
| Application | WB
|
| Primary Accession | P35869 |
| Other Accession | NP_001612 |
| Reactivity | Human |
| Isotype | IgG1 Kappa |
| Clone Names | 3H4 |
| Calculated MW | 96147 Da |
AHR Antibody (monoclonal) (M03) - Additional info | |
| Gene ID 196 | |
| Other Names aryl hydrocarbon receptor | |
| Target/Specificity AHR (NP_001612, 721 a.a. ~ 821 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. | |
| Dilution WB~~1:500~1000 | |
| Format Clear, colorless solution in phosphate buffered saline, pH 7.2 . | |
| Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. | |
| Precautions AHR Antibody (monoclonal) (M03) is for research use only and not for use in diagnostic or therapeutic procedures. | |
AHR Antibody (monoclonal) (M03) - Related products
AP5533c: AHR Antibody (Center)
BP5533c: AHR Antibody (Center) Blocking peptide
AHR Antibody (monoclonal) (M03) - Application data
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Western Blot analysis of AHR expression in transfected 293T cell line by AHR monoclonal antibody (M03), clone 3H4.
Lane 1: AHR transfected lysate(96.1 KDa).
Lane 2: Non-transfected lysate. -
Detection limit for recombinant GST tagged AHR is approximately 0.1ng/ml as a capture antibody.
AHR Antibody (monoclonal) (M03) - Research Areas
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BACKGROUND
This gene encodes a ligand-activated transcription factor involved in the regulation of biological responses to planar aromatic hydrocarbons. This receptor has been shown to regulate xenobiotic-metabolizing enzymes such as cytochrome P450. Its ligands included a variety of aromatic hydrocarbons.
REFERENCES
Activation of the aryl hydrocarbon receptor induces human type 1 regulatory T cell-like and Foxp3(+) regulatory T cells. Gandhi R, et al. Nat Immunol, 2010 Sep. PMID 20676092.Maternal genes and facial clefts in offspring: a comprehensive search for genetic associations in two population-based cleft studies from Scandinavia. Jugessur A, et al. PLoS One, 2010 Jul 9. PMID 20634891.Aryl hydrocarbon receptor is a transcriptional activator of the human breast cancer resistance protein (BCRP/ABCG2). Tan KP, et al. Mol Pharmacol, 2010 Aug. PMID 20460431.A Large-scale genetic association study of esophageal adenocarcinoma risk. Liu CY, et al. Carcinogenesis, 2010 Jul. PMID 20453000.The human AHR: identification of single nucleotide polymorphisms from six ethnic populations. Rowlands CJ, et al. Pharmacogenet Genomics, 2010 May. PMID 20401977.
