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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   AKAP10 Antibody (monoclonal) (M04)   

AKAP10 Antibody (monoclonal) (M04)

Mouse monoclonal antibody raised against a partial recombinant AKAP10.

  • WB - AKAP10 Antibody (monoclonal) (M04) AT1082a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (36.74 KDa) .
  • WB - AKAP10 Antibody (monoclonal) (M04) AT1082a
    AKAP10 monoclonal antibody (M04), clone 8C10. Western Blot analysis of AKAP10 expression in Raw 264.7.
  • WB - AKAP10 Antibody (monoclonal) (M04) AT1082a
    Western Blot analysis of AKAP10 expression in transfected 293T cell line by AKAP10 monoclonal antibody (M04), clone 8C10.

    Lane 1: AKAP10 transfected lysate(73.8 KDa).
    Lane 2: Non-transfected lysate.
  • IHC - AKAP10 Antibody (monoclonal) (M04) AT1082a
    Immunoperoxidase of monoclonal antibody to AKAP10 on formalin-fixed paraffin-embedded human testis. [antibody concentration 0.5 ug/ml]
  • E - AKAP10 Antibody (monoclonal) (M04) AT1082a
    Detection limit for recombinant GST tagged AKAP10 is approximately 0.03ng/ml as a capture antibody.
  • WB - AKAP10 Antibody (monoclonal) (M04) AT1082a
    Western blot analysis of AKAP10 over-expressed 293 cell line, cotransfected with AKAP10 Validated Chimera RNAi ( (Cat # AT1082a )
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O43572
Other Accession NM_007202
Reactivity Human, Mouse
Host mouse
Clonality Monoclonal
Isotype IgG2a Kappa
Clone Names 8C10
Calculated MW 73818 Da
Additional Information
Gene ID 11216
Other Names A-kinase anchor protein 10, mitochondrial, AKAP-10, Dual specificity A kinase-anchoring protein 2, D-AKAP-2, Protein kinase A-anchoring protein 10, PRKA10, AKAP10
Target/Specificity AKAP10 (NP_009133, 1 a.a. ~ 100 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsAKAP10 Antibody (monoclonal) (M04) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
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The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein interacts with both the type I and type II regulatory subunits of PKA; therefore, it is a dual-specific AKAP. This protein is highly enriched in mitochondria. It contains RGS (regulator of G protein signalling) domains, in addition to a PKA-RII subunit-binding domain. The mitochondrial localization and the presence of RGS domains may have important implications for the function of this protein in PKA and G protein signal transduction.


1.D-AKAP2 interacts with Rab4 and Rab11 through its RGS domains and regulates transferrin receptor recycling.Eggers CT, Schafer JC, Goldenring JR, Taylor SS.J Biol Chem. 2009 Nov 20;284(47):32869-80. Epub 2009 Sep 21.

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$ 315.00
Cat# AT1082a
(40 western blots)
Availability: 7-10 days
Bulk Size
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